Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTL | Q8NG68 | 10/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8733662 | 0.86 | TTL (0.51) | TTLMAPTPOLB | |
| SCHEMBL8733664 | 0.86 | TTL (0.51) | TTLMAPTPOLB | |
| SCHEMBL29551597 | 0.80 | MAPT (0.40) | MAPTPOLBCYP3A4TRPC6TP53 | |
| SCHEMBL29922526 | 0.80 | MAPT (0.40) | MAPTPOLBCYP3A4TRPC6TP53 | |
| SCHEMBL8731622 | 0.80 | MAPT (0.40) | MAPTPOLBCYP3A4TRPC6TP53 | |
| SCHEMBL18089046 | 0.76 | ALDH1A1 (0.57) | MAPTPOLBCYP3A4MEN1ALDH1A1 | |
| SCHEMBL15220009 | 0.76 | ALDH1A1 (0.57) | MAPTPOLBCYP3A4MEN1ALDH1A1 | |
| SCHEMBL8731628 | 0.76 | ALDH1A1 (0.57) | MAPTPOLBCYP3A4MEN1ALDH1A1 | |
| SCHEMBL9549996 | 0.76 | ALDH1A1 (0.57) | MAPTPOLBCYP3A4MEN1ALDH1A1 | |
| SCHEMBL541382 | 0.76 | ALDH1A1 (0.57) | MAPTPOLBCYP3A4MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773005-A | ENZYME INHIBITORS, ANTISECRETORY AGENTS AND ANTIANDROGENS | KABUSHIKI KAISHA YAKURIGAKU CHUO KENKYUSHO (JP) | 1998-06-30 | — | — | US | claimed |
| US-5773005-A | ENZYME INHIBITORS, ANTISECRETORY AGENTS AND ANTIANDROGENS | KABUSHIKI KAISHA YAKURIGAKU CHUO KENKYUSHO (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0747048-A2 | Diterpenes and flavonoids as 5-alpha-reductase inhibitors | Kabushiki Kaisha Yakurigaku Chuo Kenkyusho (JP) | 1996-12-11 | — | — | EP | disclosed |