Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 7/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CDC25A | P30304 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 4/20 | 0.40 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28362756 | 0.91 | ABCB1 (0.45) | ABCB1ABCG2SYKCDC25BRAB9A | |
| SCHEMBL29922810 | 0.91 | ABCB1 (0.45) | ABCB1ABCG2SYKCDC25BRAB9A | |
| SCHEMBL29551921 | 0.91 | ABCB1 (0.45) | ABCB1ABCG2SYKCDC25BRAB9A | |
| SCHEMBL29552236 | 0.82 | ABCB1 (0.43) | ABCB1ABCG2SLC7A5CDC25BRAB9A | |
| SCHEMBL29551926 | 0.79 | SYK (0.40) | SYKMEN1KMT2A | |
| SCHEMBL29922602 | 0.78 | SYK (0.43) | ABCG2SYKCDC25BMAPTCDC25A | |
| SCHEMBL28362546 | 0.78 | SYK (0.43) | ABCG2SYKCDC25BMAPTCDC25A | |
| SCHEMBL29552807 | 0.76 | SYK (0.41) | SYKMAPTALDH1A1KMT2A | |
| SCHEMBL28358863 | 0.74 | ABCB1 (0.41) | ABCB1ABCG2RAB9AMAPTALDH1A1 | |
| SCHEMBL5928315 | 0.72 | ABCG2 (0.64) | ABCB1ABCG2SLC7A5RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022032484-A1 | PYRIDAZINE-3-FORMAMIDE COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 北京诺诚健华医药科技有限公司 | 2022-02-17 | — | — | WO | disclosed |