Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.57 |
| ▸ | GAA | P10253 | 5/20 | 0.57 |
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38964 | 0.87 | ALDH1A1 (0.57) | ALDH1A1GAATSHRLMNAMAPK1 | |
| SCHEMBL14571987 | 0.87 | MAPT (0.53) | ALDH1A1GAATSHRLMNAMAPK1 | |
| SCHEMBL9478510 | 0.85 | ALDH1A1 (0.55) | ALDH1A1GAATSHRLMNAMAPK1 | |
| Hydrogen Sulfide SCHEMBL28290635 | 0.85 | ALDH1A1 (0.55) | ALDH1A1GAATSHRLMNAMAPK1 | |
| SCHEMBL9507166 | 0.83 | ALDH1A1 (0.53) | ALDH1A1GAATSHRLMNAMAPK1 | |
| SCHEMBL27379019 | 0.82 | ALDH1A1 (0.52) | ALDH1A1GAATSHRLMNAMAPK1 | |
| Bicarbonate SCHEMBL11433304 | 0.80 | ALDH1A1 (0.50) | ALDH1A1GAATSHRLMNAMAPK1 | |
| SCHEMBL9507159 | 0.80 | ALDH1A1 (0.50) | ALDH1A1GAATSHRLMNAMAPK1 | |
| SCHEMBL18476242 | 0.80 | ALDH1A1 (0.59) | ALDH1A1GAATSHRLMNAMAPK1 | |
| SCHEMBL284696 | 0.79 | ALDH1A1 (0.63) | ALDH1A1GAATSHRLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10759780-B2 | Hindered amines | 3V SIGMA S.P.A. (IT) | 2020-09-01 | — | — | US | disclosed |
| US-20200239629-A1 | HINDERED POLYMERIC AMINES | 3V SIGMA S.P.A. (IT) | 2020-07-30 | — | — | US | disclosed |
| EP-3424977-B1 | HINDERED POLYMERIC AMINES | 3V SIGMA SPA (IT) | 2020-03-18 | — | — | EP | disclosed |
| EP-3428156-B1 | HINDERED AMINES | 3V SIGMA SPA (IT) | 2020-02-12 | — | — | EP | disclosed |
| US-20190016702-A1 | HINDERED AMINES | 3V SIGMA S.P.A. (IT) | 2019-01-17 | — | — | US | disclosed |
| EP-3428156-A1 | HINDERED AMINES | 3V SIGMA S.p.A (IT) | 2019-01-16 | — | — | EP | disclosed |
| EP-3424977-A1 | HINDERED POLYMERIC AMINES | 3V SIGMA S.p.A (IT) | 2019-01-09 | — | — | EP | disclosed |
| US-20190002631-A1 | HINDERED POLYMERIC AMINES | 3V SIGMA S.P.A. (IT) | 2019-01-03 | — | — | US | disclosed |
| US-9725578-B2 | Sterically hindered polymeric amines and their use as polymer stabilizers | 3V SIGMA S.P.A. (IT) | 2017-08-08 | — | — | US | disclosed |
| EP-2632914-B1 | NEW STERICALLY HINDERED POLYMERIC AMINES AND THEIR USE AS POLYMER STABILIZERS | 3V SIGMA SPA (IT) | 2015-12-16 | — | — | EP | disclosed |
| EP-2366732-A2 | Mixtures of sterically hindered amines for polymer stabilisation | 3V SIGMA S.p.A (IT) | 2011-09-21 | — | — | EP | disclosed |
| US-20110224336-A1 | MIXTURES OF STERICALLY HINDERED AMINES FOR POLYMER STABILIZATION | 3V SIGMA S.P.A. (IT) | 2011-09-15 | — | — | US | disclosed |
| US-8003718-B2 | Oligomeric sterically hindered amines and their use as polymer stabilisers | 3V SIGMA S.P.A. (IT) | 2011-08-23 | — | — | US | disclosed |
| US-20100204371-A1 | STERICALLY HINDERED AMINES AND USE THEREOF AS POLYMER STABILIZERS | 3V SIGMA S.P.A. (IT) | 2010-08-12 | — | — | US | disclosed |
| EP-2216364-A1 | Sterically hindered amines and use thereof as polymer stabilizers | 3V SIGMA S.p.A (IT) | 2010-08-11 | — | — | EP | disclosed |
| US-7713444-B2 | Mixtures of sterically hindered amines for the stabilisation of polymers | 3V SIGMA S.P.A. (IT) | 2010-05-11 | — | — | US | disclosed |
| US-20090270535-A1 | MIXTURES OF STERICALLY HINDERED AMINES FOR THE STABILISATION OF POLYMERS | 3V SIGMA S.P.A. (IT) | 2009-10-29 | — | — | US | disclosed |
| US-20090270536-A1 | OLIGOMERIC STERICALLY HINDERED AMINES AND THEIR USE AS POLYMER STABILISERS | 3V SIGMA S.P.A. (IT) | 2009-10-29 | — | — | US | disclosed |
| EP-2112141-A1 | Oligomeric sterically hindered amines and their use as polymer stabilizers | 3V SIGMA S.p.A (IT) | 2009-10-28 | — | — | EP | disclosed |
| EP-2112198-A1 | Mixtures of sterically hindered amines for the stabilisation of polymers | 3V SIGMA S.p.A (IT) | 2009-10-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200239629-A1 | HINDERED POLYMERIC AMINES | PARG, PARN, PUF60 | ALDH1A1 884/4885GAA 1653/4885TSHR 4680/4885 |
| US-20100204371-A1 | STERICALLY HINDERED AMINES AND USE THEREOF AS POLYMER STABILIZERS | CBR3, SIGMAR1, NPSR1 | ALDH1A1 861/4885GAA 4381/4885TSHR 549/4885 |
| US-20090270536-A1 | OLIGOMERIC STERICALLY HINDERED AMINES AND THEIR USE AS POLYMER STABILISERS | PCBP1, PARG, PARN | ALDH1A1 1222/4885GAA 728/4885TSHR 4767/4885 |
| US-20190016702-A1 | HINDERED AMINES | PARG, TAAR5, PARN | ALDH1A1 638/4885GAA 2519/4885TSHR 3268/4885 |
| US-10759780-B2 | Hindered amines | PARG, TAAR5, PARN | ALDH1A1 638/4885GAA 2519/4885TSHR 3268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.