SCHEMBL29555158

SCHEMBL29555158

Cc1ccc(C(=O)O)cc1O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.64
CA12 O43570 2/20 0.64
CA1 P00915 2/20 0.64
CA2 P00918 2/20 0.64
MAPT P10636 2/20 0.64
CA4 P22748 2/20 0.64
CA6 P23280 2/20 0.64
CA7 P43166 2/20 0.64
CA9 Q16790 2/20 0.64
CA14 Q9ULX7 2/20 0.64
POLB P06746 1/20 0.64
GAA P10253 1/20 0.64
PTGS2 P35354 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
MYC P01106 3/20 0.56
TSHR P16473 3/20 0.53
HTT P42858 1/20 0.52
ALDH1A1 P00352 3/20 0.50
TDP1 Q9NUW8 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL71388 1.00 KDM4E (0.64) KDM4ECA12CA1CA2MAPT
SCHEMBL1758255 0.84 HTT (0.61) MAPTPOLBTSHRHTTALDH1A1
Triethylene Glycol SCHEMBL11021539 0.83 CA12 (0.46) KDM4ECA12CA1CA2MAPT
SCHEMBL29979976 0.82 CA12 (0.64) KDM4ECA12CA1CA2MAPT
SCHEMBL1550819 0.82 PKM (0.52) MAPTPOLBGAATSHRHTT
SCHEMBL172420 0.82 CA12 (0.64) KDM4ECA12CA1CA2MAPT
SCHEMBL29421064 0.81 CES2 (0.63) KDM4ECA12CA1CA2MAPT
SCHEMBL310259 0.81 CES2 (0.63) KDM4ECA12CA1CA2MAPT
SCHEMBL4276908 0.80 TRPA1 (0.47) KDM4ECA12CA1CA2MAPT
SCHEMBL1805871 0.80 LCK (0.53) KDM4ECA1CA2MAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4712958-A2 USE OF UROLITHIN DERIVATIVES IN THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS Vandria SA (CH) 2026-03-25 EP disclosed
EP-4630423-A1 COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS Third Harmonic Bio, Inc. (US) 2025-10-15 EP disclosed
EP-4561976-A2 UROLITHIN AND FLUORENE DERIVATIVES FOR INHIBITING FERROPTOSIS Vandria SA (CH) 2025-06-04 EP disclosed
WO-2025023241-A1 ETCHING LIQUID AND PRODUCTION METHOD FOR SEMICONDUCTOR DEVICE USING SAME 三菱瓦斯化学株式会社 2025-01-30 WO disclosed
WO-2024236367-A2 USE OF UROLITHIN DERIVATIVES IN THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS VANDRIA SA (CH) 2024-11-21 WO disclosed
WO-2024123966-A1 COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS THIRD HARMONIC BIO, INC. (US) 2024-06-13 WO disclosed
WO-2024023585-A2 UROLITHIN DERIVATIVES AND THERAPEUTIC USES VANDRIA SA (CH) 2024-02-01 WO disclosed
WO-2022078152-A1 BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF 杭州中美华东制药有限公司 2022-04-21 WO disclosed