Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29053161 | 0.78 | AGTR1 (0.41) | MEN1KMT2AGAARAB9ATDP1 | |
| SCHEMBL29555329 | 0.78 | AGTR1 (0.41) | MEN1KMT2AGAARAB9ATDP1 | |
| SCHEMBL25340079 | 0.75 | ACSS2 (0.43) | ALDH1A1PKMHTT | |
| SCHEMBL29946034 | 0.75 | ACSS2 (0.43) | ALDH1A1PKMHTT | |
| SCHEMBL25005481 | 0.73 | PDE2A (0.41) | MEN1KMT2ALMNARAB9AALDH1A1 | |
| SCHEMBL29924247 | 0.73 | PDE2A (0.41) | MEN1KMT2ALMNARAB9AALDH1A1 | |
| SCHEMBL7741401 | 0.72 | MEN1 (0.59) | MEN1KMT2ALMNAGAARAB9A | |
| SCHEMBL31183018 | 0.72 | MEN1 (0.68) | MEN1KMT2ALMNAGAACYP1A2 | |
| SCHEMBL4155796 | 0.72 | MEN1 (0.68) | MEN1KMT2ALMNAGAACYP1A2 | |
| SCHEMBL4766707 | 0.72 | MEN1 (0.62) | MEN1KMT2ALMNAGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078152-A1 | BENZIMIDAZOLONE GLP-1 RECEPTOR AGONIST AND USE THEREOF | 杭州中美华东制药有限公司 | 2022-04-21 | — | — | WO | disclosed |