Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMARCA2 | P51531 | 4/20 | 0.47 |
| ▸ | SMARCA4 | P51532 | 3/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29556285 | 0.90 | MEN1 (0.52) | RAB9ANPC1SMN1; SMN2TP53NFKB1 | |
| SCHEMBL29556176 | 0.87 | RAB9A (0.65) | RAB9ANPC1SMN1; SMN2TP53NFKB1 | |
| SCHEMBL29556948 | 0.84 | NPC1 (0.47) | RAB9ANPC1SMN1; SMN2TP53NFKB1 | |
| SCHEMBL29557088 | 0.84 | SMARCA2 (0.45) | RAB9ANPC1SMN1; SMN2TP53NFKB1 | |
| SCHEMBL10719644 | 0.84 | SMARCA2 (0.69) | RAB9ANPC1SMN1; SMN2TP53NFKB1 | |
| SCHEMBL30318910 | 0.83 | TAAR1 (0.61) | RAB9ANPC1SMN1; SMN2TP53LMNA | |
| SCHEMBL10344917 | 0.83 | TAAR1 (0.61) | RAB9ANPC1SMN1; SMN2TP53LMNA | |
| SCHEMBL22125175 | 0.82 | SMARCA2 (0.71) | LMNAKMT2AMEN1TAAR1SMARCA2 | |
| SCHEMBL29556275 | 0.80 | S1PR2 (0.48) | RAB9ANPC1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL27193043 | 0.80 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078533-A1 | SUBSTITUTED 1,3-DIPHENYLUREA DERIVATIVES AND 1-PHENYL-3-PYRIDYLUREA DERIVATIVES FOR PLANT BIOTECHNOLOGY, PREPARATIONS CONTAINING THESE COMPOUNDS AND USE THEREOF | USTAV EXPERIMENTALNI BOTANIKY AV CR, V.V.I. (CZ) | 2022-04-21 | — | — | WO | disclosed |