Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | IDH1 | O75874 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29555881 | 0.97 | RAB9A (0.46) | RAB9AMAPTNPC1HTTSMN1; SMN2 | |
| SCHEMBL29556399 | 0.94 | RAB9A (0.46) | RAB9AMAPTNPC1HTTSMN1; SMN2 | |
| SCHEMBL29556797 | 0.94 | RAB9A (0.49) | RAB9AMAPTNPC1HTTSMN1; SMN2 | |
| SCHEMBL29555889 | 0.89 | MAPT (0.56) | RAB9AMAPTNPC1HTTSMN1; SMN2 | |
| SCHEMBL29556232 | 0.89 | RAB9A (0.52) | RAB9AMAPTNPC1HTTSMN1; SMN2 | |
| SCHEMBL29557053 | 0.88 | RAB9A (0.47) | RAB9AMAPTNPC1HTTSMN1; SMN2 | |
| SCHEMBL29556244 | 0.88 | TP53 (0.55) | RAB9AMAPTNPC1HTTSMN1; SMN2 | |
| SCHEMBL29556193 | 0.85 | MAPT (0.60) | RAB9AMAPTNPC1HTTSMN1; SMN2 | |
| SCHEMBL29555591 | 0.84 | MEN1 (0.61) | RAB9AMAPTNPC1HTTKMT2A | |
| SCHEMBL29555992 | 0.84 | MEN1 (0.56) | RAB9AMAPTNPC1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078533-A1 | SUBSTITUTED 1,3-DIPHENYLUREA DERIVATIVES AND 1-PHENYL-3-PYRIDYLUREA DERIVATIVES FOR PLANT BIOTECHNOLOGY, PREPARATIONS CONTAINING THESE COMPOUNDS AND USE THEREOF | USTAV EXPERIMENTALNI BOTANIKY AV CR, V.V.I. (CZ) | 2022-04-21 | — | — | WO | disclosed |