Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29556017 | 0.89 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2KMT2APOLB | |
| SCHEMBL29556385 | 0.89 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2KMT2APOLB | |
| SCHEMBL29556797 | 0.89 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2KMT2APOLB | |
| SCHEMBL29556399 | 0.89 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2KMT2APOLB | |
| SCHEMBL29556591 | 0.88 | TP53 (0.60) | RAB9ANPC1SMN1; SMN2KMT2AHTT | |
| SCHEMBL29556574 | 0.86 | S1PR2 (0.60) | RAB9ANPC1SMN1; SMN2KMT2APOLB | |
| SCHEMBL17102381 | 0.86 | SMN1; SMN2 (0.50) | RAB9ANPC1SMN1; SMN2KMT2APOLB | |
| SCHEMBL29556598 | 0.85 | TP53 (0.70) | RAB9ANPC1SMN1; SMN2KMT2AHTT | |
| SCHEMBL29555881 | 0.85 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2KMT2APOLB | |
| SCHEMBL29556193 | 0.83 | MAPT (0.60) | RAB9ANPC1SMN1; SMN2KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078533-A1 | SUBSTITUTED 1,3-DIPHENYLUREA DERIVATIVES AND 1-PHENYL-3-PYRIDYLUREA DERIVATIVES FOR PLANT BIOTECHNOLOGY, PREPARATIONS CONTAINING THESE COMPOUNDS AND USE THEREOF | USTAV EXPERIMENTALNI BOTANIKY AV CR, V.V.I. (CZ) | 2022-04-21 | — | — | WO | disclosed |