Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 5/20 | 0.45 |
| ▸ | SMARCA4 | P51532 | 4/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29555620 | 0.84 | AR (0.49) | SMARCA2SMARCA4MAPK14KMT2AMEN1 | |
| SCHEMBL29556405 | 0.84 | RAB9A (0.49) | SMARCA2SMARCA4KMT2AMEN1TAAR1 | |
| SCHEMBL29555847 | 0.81 | SMARCA2 (0.69) | SMARCA2SMARCA4MAPK14KMT2AMEN1 | |
| SCHEMBL10344917 | 0.81 | TAAR1 (0.61) | SMARCA2SMARCA4KMT2AMEN1TAAR1 | |
| SCHEMBL30318910 | 0.81 | TAAR1 (0.61) | SMARCA2SMARCA4KMT2AMEN1TAAR1 | |
| SCHEMBL22125175 | 0.79 | SMARCA2 (0.71) | SMARCA2SMARCA4KMT2AMEN1TAAR1 | |
| SCHEMBL23832005 | 0.79 | KCNH2 (0.39) | SMARCA2SMARCA4KMT2AMEN1TAAR1 | |
| SCHEMBL29556176 | 0.78 | RAB9A (0.65) | KMT2AMEN1TAAR1LMNAMAPT | |
| SCHEMBL29556285 | 0.78 | MEN1 (0.52) | SMARCA2SMARCA4KMT2AMEN1LMNA | |
| SCHEMBL23832117 | 0.77 | KMT2A (0.44) | SMARCA2SMARCA4KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078533-A1 | SUBSTITUTED 1,3-DIPHENYLUREA DERIVATIVES AND 1-PHENYL-3-PYRIDYLUREA DERIVATIVES FOR PLANT BIOTECHNOLOGY, PREPARATIONS CONTAINING THESE COMPOUNDS AND USE THEREOF | USTAV EXPERIMENTALNI BOTANIKY AV CR, V.V.I. (CZ) | 2022-04-21 | — | — | WO | disclosed |