Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 7/20 | 0.45 |
| ▸ | MMP2 | P08253 | 5/20 | 0.45 |
| ▸ | MMP9 | P14780 | 5/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28472846 | 1.00 | ADAM17 (0.45) | ADAM17MMP2MMP9BCHEACHE | |
| SCHEMBL28389052 | 0.93 | ADAM17 (0.43) | ADAM17MMP2MMP9BCHEACHE | |
| SCHEMBL29599436 | 0.91 | ADAM17 (0.46) | ADAM17MMP2MMP9ACHENQO1 | |
| SCHEMBL28453762 | 0.91 | ADAM17 (0.46) | ADAM17MMP2MMP9ACHENQO1 | |
| SCHEMBL28435430 | 0.78 | KDM4E (0.45) | ADAM17MMP2MMP9KMT2AKDM4E | |
| SCHEMBL28477622 | 0.75 | ACHE (0.58) | BCHEACHEKMT2AKDM4EMEN1 | |
| SCHEMBL29558409 | 0.75 | ACHE (0.58) | BCHEACHEKMT2AKDM4EMEN1 | |
| SCHEMBL28384459 | 0.74 | NQO1 (0.52) | NQO1KMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL28754205 | 0.74 | HSD17B3 (0.54) | ADAM17MMP2MMP9KMT2AKDM4E | |
| SCHEMBL29089438 | 0.73 | ADAM17 (0.64) | ADAM17MMP2MMP9KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111423406-B | Pyranolactone compound and preparation method and application thereof | 云南中烟工业有限责任公司 | 2022-05-13 | — | — | CN | disclosed |