Vialinin A

Vialinin A

SCHEMBL29559604

O=C(Cc1ccccc1)Oc1c(OC(=O)Cc2ccccc2)c(-c2ccc(O)cc2)c(O)c(O)c1-c1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SENP1 Q9P0U3 3/20 1.00
UCHL1 P09936 1/20 1.00
USP5 P45974 1/20 1.00
USP4 Q13107 1/20 1.00
PREP P48147 2/20 0.55
SMN1; SMN2 Q16637 1/20 0.53
FNTA P49354 1/20 0.49
FNTB P49356 1/20 0.49
CELA1 Q9UNI1 1/20 0.47
ALDH1A1 P00352 1/20 0.47
MAPK1 P28482 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
PDE4A P27815 2/20 0.43
PDE4B Q07343 2/20 0.43
PDE4C Q08493 2/20 0.43
PDE4D Q08499 2/20 0.43
ASAH1 Q13510 1/20 0.43
PAM P19021 1/20 0.42
CYP19A1 P11511 1/20 0.42
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Vialinin B SCHEMBL29711168 0.79 SENP1 (0.63) SENP1UCHL1USP5USP4PREP
SCHEMBL417740 0.77 SENP1 (0.62) SENP1UCHL1USP5USP4SMN1; SMN2
SCHEMBL417739 0.74 CYP19A1 (0.67) SENP1UCHL1USP5USP4SMN1; SMN2
SCHEMBL29711334 0.73 SENP1 (0.58) SENP1UCHL1USP5USP4PREP
SCHEMBL2637879 0.70 ASAH1 (0.68) SENP1UCHL1USP5USP4SMN1; SMN2
SCHEMBL6937307 0.70 SMN1; SMN2 (0.67) SENP1UCHL1USP5USP4SMN1; SMN2
SCHEMBL57331 0.70 ALDH1A1 (0.85) SENP1UCHL1USP5USP4FNTA
SCHEMBL8862346 0.69 CYP19A1 (0.56) SENP1UCHL1USP5USP4SMN1; SMN2
SCHEMBL31226071 0.69 SENP1 (0.61) SENP1UCHL1USP5USP4SMN1; SMN2
SCHEMBL10573912 0.69 MAPK1 (0.61) SENP1UCHL1USP5USP4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025030135-A2 METHODS FOR TREATING AND AMELIORATING ANGINA, MYOCARDIAL INFARCTION, REPERFUSION INJURY, HEART ARRHYTHMIAS AND CONGESTIVE HEART FAILURE (CHF) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-02-06 WO claimed
WO-2025029578-A1 SUMOYLATION AS A THERAPEUTIC TARGET IN INFLAMMATORY BOWEL DISEASES AND INFECTIONS DISORDERS DUKE UNIVERSITY (US) 2025-02-06 WO claimed
WO-2024249339-A1 COMBINED RTK AND SUMO INHIBITION FOR CANCER THERAPY THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-12-05 WO claimed
US-20240358731-A1 SUMO PATHWAY AS AN OXYGEN SENSOR RELEVANT TO THE PATHOPHYSIOLOGY OF PULMONARY ARTERY HYPERTENSION AND CARDIAC ARRHYTHMIA NORTHEASTERN UNIVERSITY 2024-10-31 US claimed
CN-118526480-A Application of USP4 inhibitor in preparation of leukemia treatment products 暨南大学 2024-08-23 CN claimed
CN-119827767-B Use of ubiquitin-specific protease USP4 for treating acute lung injury/acute respiratory distress syndrome 重庆医科大学 2025-10-28 CN disclosed
CN-119827767-A Use of ubiquitin-specific protease USP4 for treating acute lung injury/acute respiratory distress syndrome 重庆医科大学 2025-04-15 CN disclosed
CN-119827767-A Use of ubiquitin-specific protease USP4 for treating acute lung injury/acute respiratory distress syndrome 重庆医科大学 2025-04-15 CN disclosed
WO-2025030135-A2 METHODS FOR TREATING AND AMELIORATING ANGINA, MYOCARDIAL INFARCTION, REPERFUSION INJURY, HEART ARRHYTHMIAS AND CONGESTIVE HEART FAILURE (CHF) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-02-06 WO disclosed
WO-2025029578-A1 SUMOYLATION AS A THERAPEUTIC TARGET IN INFLAMMATORY BOWEL DISEASES AND INFECTIONS DISORDERS DUKE UNIVERSITY (US) 2025-02-06 WO disclosed
CN-222379009-U Detection device and intelligent terminal 上海传英信息技术有限公司 2025-01-21 CN disclosed
CN-119299561-A Control method, intelligent terminal and storage medium 深圳传音控股股份有限公司 2025-01-10 CN disclosed
CN-219417963-U Multicolor electric control color-changing device, shell assembly and intelligent terminal 深圳传音控股股份有限公司 2023-07-25 CN disclosed
CN-108966250-B Weak signal communication method, mobile terminal and computer readable storage medium 山东沃伦通信技术有限公司 2023-07-07 CN disclosed
CN-116185549-A Processing method, intelligent terminal and storage medium 上海传英信息技术有限公司 2023-05-30 CN disclosed
CN-116069887-A Information processing method, intelligent terminal and storage medium 上海传英信息技术有限公司 2023-05-05 CN disclosed
CN-115993926-A Interaction method, intelligent terminal and storage medium 上海传英信息技术有限公司 2023-04-21 CN disclosed
US-20230123585-A1 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING CANCER USING DEUBIQUITINASE INHIBITORS UNIV CHICAGO (US) 2023-04-20 US disclosed
CN-110248932-B Pyrimidine tricycloalkenone derivatives for ROR γ inhibition and other uses 里亚塔医药公司 2023-03-10 CN disclosed
CN-114072000-A Molecules having certain pesticidal effects and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2022-02-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240358731-A1 SUMO PATHWAY AS AN OXYGEN SENSOR RELEVANT TO THE PATHOPHYSIOLOGY OF PULMONARY ARTERY HYPERTENSION AND CARDIAC ARRHYTHMIA SUMO1, SUMO2, SUMO3 SENP1 10/4885UCHL1 930/4885USP5 117/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.