Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.54 |
| ▸ | USP5 | P45974 | 1/20 | 0.54 |
| ▸ | USP4 | Q13107 | 1/20 | 0.54 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PAM | P19021 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31225490 | 0.90 | SMN1; SMN2 (0.55) | SMN1; SMN2UCHL1USP5USP4SENP1 | |
| SCHEMBL26011690 | 0.88 | SMN1; SMN2 (0.61) | SMN1; SMN2UCHL1USP5USP4SENP1 | |
| SCHEMBL31226055 | 0.85 | KMT2A (0.55) | SMN1; SMN2SENP1ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL31226071 | 0.84 | SENP1 (0.61) | SMN1; SMN2UCHL1USP5USP4SENP1 | |
| SCHEMBL9059841 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2UCHL1USP5USP4SENP1 | |
| SCHEMBL31225718 | 0.83 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPK1ALDH1A1POLB | |
| SCHEMBL20869833 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2UCHL1USP5USP4SENP1 | |
| SCHEMBL22499185 | 0.82 | TDP1 (0.58) | SMN1; SMN2TSHRALDH1A1L3MBTL1KMT2A | |
| SCHEMBL31225821 | 0.82 | KMT2A (0.52) | SMN1; SMN2SENP1TSHRALDH1A1L3MBTL1 | |
| SCHEMBL31225807 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2UCHL1USP5USP4SENP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003091210-A1 | A NEW SYNTHESIS FOR THE PREPARATION OF PORPHOBILINOGEN AND THE COMPOUND AS SUCH AS STABILIZED SALT AND INTERMEDIATES THEREOF | NEIER REINHARD (CH) | 2003-11-06 | — | — | WO | claimed |
| EP-1357110-A1 | Synthesis for the preparation of porphobilinogen, the compound as such as stabilized salt and intermediates thereof | Neier, Reinhard (CH) | 2003-10-29 | — | — | EP | claimed |
| CN-1282640-C | N-arylphenylacetamide derivatives and medicinal compositions containing same | DAINIPPON PHARMACEUTICAL CO (JP) | 2006-11-01 | — | — | CN | disclosed |
| CN-1529692-A | N-arylphenylacetamide derivatives and medicinal compositions containing same | 大日本制药株式会社 | 2004-09-15 | — | — | CN | disclosed |
| WO-2003091210-A1 | A NEW SYNTHESIS FOR THE PREPARATION OF PORPHOBILINOGEN AND THE COMPOUND AS SUCH AS STABILIZED SALT AND INTERMEDIATES THEREOF | NEIER REINHARD (CH) | 2003-11-06 | — | — | WO | disclosed |
| EP-1357110-A1 | Synthesis for the preparation of porphobilinogen, the compound as such as stabilized salt and intermediates thereof | Neier, Reinhard (CH) | 2003-10-29 | — | — | EP | disclosed |
| CN-1391473-A | VLA-4 inhibitor compounds | DAIICHI SEIYAKU CO (JP) | 2003-01-15 | — | — | CN | disclosed |