Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1581001 | 0.77 | ADRA2A (0.44) | LOXL2ADRA2AADRA2BADRA2CMAPT | |
| SCHEMBL4749637 | 0.77 | ADRA2A (0.32) | ADRA2AADRA2BADRA2CMAPTLMNA | |
| Hydrochloric Acid SCHEMBL7848303 | 0.76 | ADRA2A (0.45) | LOXL2ADRA2AADRA2BADRA2CMAPT | |
| SCHEMBL2625493 | 0.72 | ALDH1A1 (0.42) | MAPTLMNAMEN1KMT2ANPC1 | |
| SCHEMBL18833848 | 0.69 | LOXL2 (0.53) | LOXL2MAPTNPC1ALDH1A1CYP1A2 | |
| SCHEMBL942066 | 0.69 | LOXL2 (0.53) | LOXL2MAPTNPC1ALDH1A1CYP1A2 | |
| SCHEMBL438963 | 0.69 | MAPT (0.64) | ADRA2AADRA2BADRA2CMAPTLMNA | |
| Hydrochloric Acid SCHEMBL1820970 | 0.68 | LOXL2 (0.52) | LOXL2MAPTNPC1ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL11740245 | 0.68 | LOXL2 (0.52) | LOXL2MAPTNPC1ALDH1A1CYP1A2 | |
| SCHEMBL15651328 | 0.67 | ALDH1A1 (0.51) | MAPTLMNAMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111943892-B | Histone deacetylase subtype inhibitor thioacetylarylamine compound and application thereof | 上海中泽医药科技有限公司 | 2022-04-05 | — | — | CN | disclosed |