Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22866783 | 1.00 | SSTR4 (0.31) | SSTR4GRM2CACNA1GCACNA1BCACNA1C | |
| SCHEMBL28718325 | 0.91 | EIF4EBP1 (0.32) | SSTR4GRM2CACNA1GCACNA1BCACNA1C | |
| SCHEMBL29661871 | 0.85 | UGT8 (0.31) | — | |
| SCHEMBL29661801 | 0.85 | UGT8 (0.31) | — | |
| SCHEMBL22866572 | 0.85 | UGT8 (0.31) | — | |
| SCHEMBL22866552 | 0.85 | UGT8 (0.31) | — | |
| SCHEMBL22866573 | 0.84 | UGT8 (0.33) | — | |
| SCHEMBL22866554 | 0.83 | PTPRB (0.33) | — | |
| SCHEMBL29561004 | 0.83 | PTPRB (0.33) | — | |
| SCHEMBL22866471 | 0.78 | L3MBTL1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269756-B | 4-Oxo-3, 4-dihydropyrido [3,4-D ] pyrimidine compounds that inhibit EIF4E | 效应疗法股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| EP-3994139-A1 | EIF4E-INHIBITING 4-OXO-3,4-DIHYDROPYRIDO[3,4-D]PYRIMIDINE COMPOUNDS | Effector Therapeutics Inc. (US) | 2022-05-11 | — | — | EP | disclosed |
| CN-114269756-A | 4-oxo-3, 4-dihydropyrido [3,4-D ] pyrimidine compounds inhibiting EIF4E | 效应疗法股份有限公司 | 2022-04-01 | — | — | CN | disclosed |