Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT8 | Q16880 | 2/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22866552 | 1.00 | UGT8 (0.31) | UGT8HPGDS | |
| SCHEMBL29661801 | 0.90 | UGT8 (0.31) | UGT8HPGDS | |
| SCHEMBL22866572 | 0.90 | UGT8 (0.31) | UGT8HPGDS | |
| SCHEMBL22866573 | 0.89 | UGT8 (0.33) | UGT8HPGDS | |
| SCHEMBL22866554 | 0.88 | PTPRB (0.33) | UGT8 | |
| SCHEMBL29561004 | 0.88 | PTPRB (0.33) | UGT8 | |
| SCHEMBL29560284 | 0.85 | SSTR4 (0.31) | — | |
| SCHEMBL22866783 | 0.85 | SSTR4 (0.31) | — | |
| SCHEMBL22866471 | 0.83 | L3MBTL1 (0.34) | HPGDS | |
| SCHEMBL22866574 | 0.80 | HPGDS (0.31) | HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3994139-A1 | EIF4E-INHIBITING 4-OXO-3,4-DIHYDROPYRIDO[3,4-D]PYRIMIDINE COMPOUNDS | Effector Therapeutics Inc. (US) | 2022-05-11 | — | — | EP | disclosed |