Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | UGT8 | Q16880 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22866554 | 1.00 | PTPRB (0.33) | PTPRBKDM4EUGT8EGFRMTNR1A | |
| SCHEMBL22866572 | 0.88 | UGT8 (0.31) | PTPRBUGT8 | |
| SCHEMBL29661801 | 0.88 | UGT8 (0.31) | PTPRBUGT8 | |
| SCHEMBL22866552 | 0.88 | UGT8 (0.31) | UGT8 | |
| SCHEMBL29661871 | 0.88 | UGT8 (0.31) | UGT8 | |
| SCHEMBL22866573 | 0.87 | UGT8 (0.33) | KDM4EUGT8 | |
| SCHEMBL22866783 | 0.83 | SSTR4 (0.31) | — | |
| SCHEMBL29560284 | 0.83 | SSTR4 (0.31) | — | |
| SCHEMBL22866471 | 0.81 | L3MBTL1 (0.34) | KDM4E | |
| SCHEMBL22866574 | 0.78 | HPGDS (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269756-B | 4-Oxo-3, 4-dihydropyrido [3,4-D ] pyrimidine compounds that inhibit EIF4E | 效应疗法股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-114269756-A | 4-oxo-3, 4-dihydropyrido [3,4-D ] pyrimidine compounds inhibiting EIF4E | 效应疗法股份有限公司 | 2022-04-01 | — | — | CN | disclosed |