Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.33 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.33 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3644681 | 1.00 | GPR3 (0.40) | GPR3HTR2APOLBACHECHRM2 | |
| Fluoride Ion SCHEMBL1130436 | 0.96 | GPR3 (0.40) | GPR3HTR2APOLBACHECHRM2 | |
| Hydrochloric Acid SCHEMBL29560931 | 0.87 | GPR3 (0.34) | GPR3HTR2APOLB | |
| Hydrochloric Acid SCHEMBL812492 | 0.86 | ELANE (0.37) | GPR3KMT2AMEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL7211638 | 0.84 | GPR3 (0.31) | GPR3 | |
| Hydrochloric Acid SCHEMBL30724644 | 0.80 | GPR3 (0.30) | GPR3 | |
| Hydrochloric Acid SCHEMBL2806872 | 0.80 | GPR3 (0.30) | GPR3 | |
| Hydrochloric Acid SCHEMBL2046475 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL7873602 | 0.79 | NR3C1 (0.44) | POLBHTR1AKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL2050242 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478316-A | Preparation method of poly alpha-olefin | 中国石油天然气股份有限公司 | 2023-07-25 | — | — | CN | claimed |
| CN-114316100-B | Boron trifluoride modified silica gel, preparation method and application thereof, supported catalyst, preparation method and application thereof | 岳阳兴长石化股份有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-114163552-B | Modified silica gel, preparation method and application thereof, supported catalyst, preparation method and application thereof | 岳阳兴长石化股份有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116478316-A | Preparation method of poly alpha-olefin | 中国石油天然气股份有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-114316100-A | Boron trifluoride modified silica gel, preparation method and application thereof, supported catalyst, preparation method and application thereof | 湖南立为新材料有限公司 | 2022-04-12 | — | — | CN | disclosed |