Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 5/20 | 0.57 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.51 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.51 |
| ▸ | BRAF | P15056 | 2/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29561778 | 0.89 | PGR (0.60) | PGRFFAR4HDAC3HDAC4HDAC1 | |
| SCHEMBL29561435 | 0.84 | PGR (0.64) | PGRCYP19A1CYP3A4 | |
| SCHEMBL14458175 | 0.82 | ALOX15 (0.64) | PGRSLC22A12CYP19A1FFAR4AVPR2 | |
| SCHEMBL29561446 | 0.82 | AVPR2 (0.55) | PGRSLC22A12AVPR2GPR27CYP3A4 | |
| SCHEMBL29562109 | 0.81 | CDK1 (0.67) | PGRCYP19A1FFAR4AVPR2GPR27 | |
| SCHEMBL29561272 | 0.80 | PGR (0.67) | PGRCYP19A1GPR27ALOX15CYP3A4 | |
| SCHEMBL29561440 | 0.79 | ALDH1A1 (0.60) | PGRCYP19A1CA1CA2CYP3A4 | |
| SCHEMBL7570765 | 0.79 | CES1 (0.67) | PGRFFAR4HDAC3HDAC4HDAC1 | |
| SCHEMBL29562342 | 0.78 | PGR (0.72) | PGRCYP19A1AVPR2GPR27CA1 | |
| SCHEMBL29561923 | 0.77 | CA1 (0.63) | PGRFFAR4CA1CA2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384694-B | SIRT6 small-molecule agonist and application thereof | 上海爱乐维生物科技有限公司 | 2022-04-05 | — | — | CN | disclosed |