Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.50 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.50 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.50 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.50 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.50 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29561470 | 0.89 | MEN1 (0.54) | MEN1KMT2ACES1CYP3A4CYP2D6 | |
| SCHEMBL29561923 | 0.87 | CA1 (0.63) | MEN1KMT2AMAPTCES1CYP3A4 | |
| SCHEMBL29561320 | 0.87 | CA1 (0.50) | MEN1KMT2AMAPTCES1CYP3A4 | |
| SCHEMBL29561493 | 0.87 | MAPT (0.50) | MEN1KMT2AMAPTCES1LMNA | |
| SCHEMBL29561505 | 0.85 | PGR (0.57) | ACLYMEN1KMT2ACES1CYP3A4 | |
| SCHEMBL29561451 | 0.85 | FFAR4 (0.52) | ACLYMEN1KMT2AMAPTCES1 | |
| SCHEMBL29561406 | 0.81 | MEN1 (0.59) | ACLYMEN1KMT2AMAPTCES1 | |
| SCHEMBL29561440 | 0.81 | ALDH1A1 (0.60) | MEN1KMT2ACES1CYP3A4CYP2D6 | |
| SCHEMBL29561893 | 0.80 | MEN1 (0.61) | ACLYMEN1KMT2AMAPTCES1 | |
| SCHEMBL29561444 | 0.79 | CES1 (0.81) | ACLYMAPTCES1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384694-B | SIRT6 small-molecule agonist and application thereof | 上海爱乐维生物科技有限公司 | 2022-04-05 | — | — | CN | disclosed |