Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | CD44 | P16070 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 3/20 | 0.30 |
| ▸ | NOS1 | P29475 | 3/20 | 0.30 |
| ▸ | NOS2 | P35228 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9938081 | 0.81 | UHRF1 (0.38) | UHRF1RXFP1CD44KDM4EKMT2A | |
| Formamide SCHEMBL8771580 | 0.73 | UHRF1 (0.32) | UHRF1KDM4EKMT2A | |
| SCHEMBL9455975 | 0.72 | AXL (0.42) | CYP3A4NOS3NOS1NOS2 | |
| SCHEMBL632541 | 0.72 | PLAU (0.36) | CYP3A4RXFP1KDM4E | |
| SCHEMBL28002235 | 0.71 | UHRF1 (0.38) | UHRF1CD44KDM4ENOS3NOS1 | |
| SCHEMBL17670982 | 0.71 | PLAU (0.37) | RXFP1CD44KDM4EKMT2ANOS3 | |
| SCHEMBL9455862 | 0.71 | NOS3 (0.39) | UHRF1RXFP1CD44KDM4EKMT2A | |
| SCHEMBL24452594 | 0.69 | — | — | |
| SCHEMBL22542673 | 0.69 | — | — | |
| SCHEMBL22542671 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008460-B | Pharmaceutically acceptable salts of 2- {4- [ (3S) -piperidin-3-yl ] phenyl } -2H-indazole-7-carboxamide | 默沙东公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-114761432-A | Dosing regimen of anti-CD 27 antibodies for treatment of cancer | 默沙东公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-110272426-B | Alkynyl (hetero) aromatic ring compounds for inhibiting protein kinase activity | 深圳市塔吉瑞生物医药有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-110194772-B | Alkynyl (hetero) aromatic ring compounds for inhibiting protein kinase activity | 深圳市塔吉瑞生物医药有限公司 | 2022-04-05 | — | — | CN | disclosed |