Formamide

Formamide

SCHEMBL8771580

Cc1ncc(N)c(C)c1Cl.NC=O

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
UHRF1 Q96T88 1/20 0.32
IDO1 P14902 1/20 0.30
KDM4E B2RXH2 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9938081 0.90 UHRF1 (0.38) UHRF1IDO1KDM4EKMT2A
Formamide SCHEMBL8771746 0.74 PIN1 (0.35) KMT2A
SCHEMBL24844536 0.73 UHRF1 (0.38) UHRF1KDM4E
SCHEMBL29561968 0.73 UHRF1 (0.38) UHRF1KDM4EKMT2A
SCHEMBL17366548 0.69 UHRF1 (0.35) UHRF1
SCHEMBL19960712 0.69 UHRF1 (0.40) UHRF1KMT2A
SCHEMBL3665628 0.69 UHRF1 (0.42) UHRF1KDM4EKMT2A
Formamide SCHEMBL29114688 0.69 UHRF1 (0.50) UHRF1KMT2A
SCHEMBL23743789 0.68 CCR1 (0.41) KDM4E
SCHEMBL12139492 0.68 PLAU (0.48) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0473267-B1 Acylaminopyridinecarboxamides, process for their preparation and their use as fungicides ZENECA LTD (GB) 1997-10-01 EP disclosed
EP-0473267-A2 Acylaminopyridinecarboxamides, process for their preparation and their use as fungicides ZENECA LIMITED (GB) 1992-03-04 EP disclosed