SCHEMBL29562248

SCHEMBL29562248

CC(C)OC(=O)CCC(=O)O[Si](OC(=O)CCC(=O)OC(C)C)(OC(C)C)OC(C)C

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
MAPT P10636 3/20 0.38
HTT P42858 1/20 0.36
TSHR P16473 4/20 0.35
NOTUM Q6P988 1/20 0.34
ALDH1A1 P00352 3/20 0.33
HSD17B10 Q99714 2/20 0.33
KDM4E B2RXH2 1/20 0.33
HPGD P15428 1/20 0.33
CYP2D6 P10635 1/20 0.31
GAA P10253 1/20 0.31
EPHX2 P34913 1/20 0.31
ALOX15 P16050 1/20 0.30
CASP1 P29466 1/20 0.30
CASP7 P55210 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10773405 0.82 ALDH1A1 (0.44) LMNAMAPTTSHRALDH1A1ALOX15
SCHEMBL72471 0.80 LMNA (0.62) LMNAMAPTHTTTSHRNOTUM
SCHEMBL3238650 0.78 LMNA (0.48) LMNAMAPTTSHRALDH1A1KDM4E
SCHEMBL31402602 0.78 LMNA (0.60) LMNAMAPTHTTTSHRNOTUM
SCHEMBL10773323 0.78 ALDH1A1 (0.44) LMNAMAPTTSHRALDH1A1ALOX15
SCHEMBL25317273 0.77 LMNA (0.32) LMNAALDH1A1ALOX15
SCHEMBL14760018 0.76 LMNA (0.46) LMNAMAPTHTTTSHRNOTUM
Butane SCHEMBL20558824 0.73 LMNA (0.68) LMNAMAPTHTTTSHRNOTUM
SCHEMBL27638144 0.73 LMNA (0.75) LMNAMAPTTSHRALDH1A1HSD17B10
SCHEMBL25182 0.73 LMNA (0.56) LMNAMAPTHTTTSHRNOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2567986-B1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF PETROCHINA CO LTD (CN) 2022-04-13 EP claimed
EP-2567986-B1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF PETROCHINA CO LTD (CN) 2022-04-13 EP disclosed