Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 5/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 5/20 | 0.48 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.43 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31539602 | 0.82 | CARM1 (0.53) | CARM1PRMT6PRMT8TMEM97SIGMAR1 | |
| SCHEMBL29562612 | 0.79 | ALOX5 (0.37) | CARM1PRMT6PRMT8TMEM97SIGMAR1 | |
| SCHEMBL16447597 | 0.76 | CARM1 (0.49) | CARM1PRMT6PRMT8TMEM97SIGMAR1 | |
| SCHEMBL28253964 | 0.75 | CARM1 (0.48) | CARM1PRMT6PRMT8TMEM97SIGMAR1 | |
| SCHEMBL16447595 | 0.74 | HRH3 (0.51) | CARM1PRMT6PRMT8TMEM97SIGMAR1 | |
| SCHEMBL24567238 | 0.74 | LIPG (0.46) | CARM1PRMT6PRMT8TMEM97SIGMAR1 | |
| SCHEMBL6469380 | 0.73 | OPRM1 (0.59) | CARM1PRMT6PRMT8TMEM97SIGMAR1 | |
| SCHEMBL11210636 | 0.72 | CARM1 (0.57) | CARM1PRMT6PRMT8TMEM97SIGMAR1 | |
| SCHEMBL5140977 | 0.72 | CARM1 (0.66) | CARM1PRMT6PRMT8TMEM97SIGMAR1 | |
| SCHEMBL27158553 | 0.72 | NPC1 (0.59) | CARM1PRMT6PRMT8TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109580-A1 | INHIBITION OF TYK2 DEPENDENT SIGNALING PATHWAYS | JANSSEN PHARMACEUTICA NV (BE) | 2022-05-27 | — | — | WO | disclosed |