Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ADH1C | P00326 | 2/20 | 0.35 |
| ▸ | ADH1A | P07327 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14902207 | 0.83 | ALDH1A1 (0.54) | ALDH1A1KMT2AATMPKMSIGMAR1 | |
| SCHEMBL15016380 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KMT2AATMPKMSIGMAR1 | |
| SCHEMBL16210731 | 0.79 | ALDH1A1 (0.50) | ALDH1A1KMT2AATMPKMSIGMAR1 | |
| SCHEMBL13826873 | 0.77 | ALDH1A1 (0.39) | ALDH1A1KMT2AADH1CADH1AATM | |
| SCHEMBL11325407 | 0.75 | TSHR (0.36) | ALDH1A1KMT2ANPSR1MEN1 | |
| SCHEMBL30876828 | 0.74 | LMNA (0.41) | ALDH1A1ADH1CADH1APKMNPSR1 | |
| SCHEMBL5069991 | 0.74 | ALDH1A1 (0.35) | ALDH1A1KMT2ANPSR1LMNAMEN1 | |
| SCHEMBL13014531 | 0.72 | ADH1A (0.41) | ALDH1A1ADH1CADH1AATMPKM | |
| SCHEMBL7805428 | 0.71 | ALDH1A1 (0.42) | ALDH1A1KMT2AADH1CADH1AATM | |
| SCHEMBL7129642 | 0.71 | ALDH1A1 (0.59) | ALDH1A1KMT2AADH1CADH1AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022091001-A1 | PROCESS FOR PREPARATION OF PALBOCICLIB | PFIZER IRELAND PHARMACEUTICALS (IE) | 2022-05-05 | — | — | WO | disclosed |