Albendazole Oxide

Albendazole Oxide

SCHEMBL29564405

CCC[S+]([O-])c1ccc2[nH]c(NC(=O)OC)nc2c1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 8/20 0.55
TUBB4A P04350 7/20 0.55
TUBB P07437 7/20 0.55
TUBA3C P0DPH7 7/20 0.55
TUBA1B P68363 7/20 0.55
TUBA4A P68366 7/20 0.55
TUBB4B P68371 7/20 0.55
TUBB3 Q13509 7/20 0.55
TUBB2A Q13885 7/20 0.55
TUBB8 Q3ZCM7 7/20 0.55
TUBA3E Q6PEY2 7/20 0.55
TUBA1A Q71U36 7/20 0.55
TUBA1C Q9BQE3 7/20 0.55
TUBB6 Q9BUF5 7/20 0.55
TUBB2B Q9BVA1 7/20 0.55
TUBB1 Q9H4B7 7/20 0.55
CYP1A2 P05177 6/20 0.55
HIF1A Q16665 5/20 0.55
TSHR P16473 2/20 0.55
CYP2D6 P10635 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Albendazole Oxide SCHEMBL321413 1.00 LMNA (0.55) LMNATUBB4ATUBBTUBA3CTUBA1B
Albendazole Oxide SCHEMBL3175532 0.99 LMNA (0.54) LMNATUBB4ATUBBTUBA3CTUBA1B
SCHEMBL11662850 0.91 LMNA (0.53) LMNATUBB4ATUBBTUBA3CTUBA1B
Albendazole Oxide SCHEMBL30580728 0.91 LMNA (0.64) LMNATUBB4ATUBBTUBA3CTUBA1B
Albendazole Oxide SCHEMBL17968582 0.91 LMNA (0.64) LMNATUBB4ATUBBTUBA3CTUBA1B
Albendazole Oxide SCHEMBL1649240 0.91 LMNA (0.64) LMNATUBB4ATUBBTUBA3CTUBA1B
Albendazole Oxide SCHEMBL9370388 0.90 LMNA (0.66) LMNATUBB4ATUBBTUBA3CTUBA1B
SCHEMBL10890981 0.88 NPC1 (0.43) LMNATUBB4ATUBBTUBA3CTUBA1B
SCHEMBL11266576 0.88 LMNA (0.45) LMNATUBB4ATUBBTUBA3CTUBA1B
SCHEMBL11213713 0.86 LMNA (0.47) LMNATUBB4ATUBBTUBA3CTUBA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024189607-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT DIDENKO KIRILL (MX) 2024-09-19 WO claimed
EP-3923988-B1 TRIAMTERENE OR NOLATREXED FOR USE IN THE TREATMENT OF PHENYLKETONURIA SOM INNOVATION BIOTECH S A (ES) 2025-04-30 EP disclosed
US-20250100947-A1 NITROUS OXIDE INHIBITOR HIS MAJESTY THE KING IN RIGHT OF NEW ZEALAND ACTING THROUGH THE MINISTRY FOR PRIMARY INDUSTRIES (NZ) 2025-03-27 US disclosed
US-12257253-B2 Triamterene or nolatrexed for use in the treatment of phenylketonuria SOM INNOVATION BIOTECH, S.A. (ES) 2025-03-25 US disclosed
CN-119405655-A Albendazole solid dispersant, and preparation method and application thereof 华南农业大学 2025-02-11 CN disclosed
CN-118948779-A Albendazole nano-crystal with high bioavailability and preparation method thereof 中国药科大学 2024-11-15 CN disclosed
CN-118908897-A Albendazole nanocrystal and preparation method thereof 中国药科大学 2024-11-08 CN disclosed
EP-4452907-A1 NITROUS OXIDE INHIBITOR His Majesty the King In Right of New Zealand Acting Through the Ministry for Primary Industries (NZ) 2024-10-30 EP disclosed
CN-118715194-A Nitrous oxide inhibitors 新西兰国王陛下通过初级产业部 2024-09-27 CN disclosed
WO-2024189607-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT DIDENKO KIRILL (MX) 2024-09-19 WO disclosed
WO-2024172666-A1 NITRIFICATION INHIBITOR NEWTON PAUL CHARLES DUMMERE (NZ) 2024-08-22 WO disclosed
EP-3607084-B1 A METHOD FOR TESTING ANTIMICROBIAL SUSCEPTIBILITY UNIV WESTERN AUSTRALIA (AU) 2024-05-01 EP disclosed
WO-2023121484-A1 NITROUS OXIDE INHIBITOR NEWTON PAUL CHARLES DUMMERE (NZ) 2023-06-29 WO disclosed
CN-116297362-A High-sensitivity, rapid and visual method for detecting albendazole and albendazole sulfoxide residues in animal-derived food 湖北工业大学 2023-06-23 CN disclosed
US-20230181463-A1 OLEOGEL AND OLEOPASTE COMPOSITIONS AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-06-15 US disclosed
CN-115919774-A Magnetic targeting nano albendazole liposome and preparation method thereof 新疆医科大学第一附属医院 2023-04-07 CN disclosed
CN-114224834-B Albendazole nano suspension with high bioavailability and preparation method thereof 沈阳伟嘉生物技术有限公司 2022-11-11 CN disclosed
US-20220133726-A1 TRIAMTERENE OR NOLATREXED FOR USE IN THE TREATMENT OF PHENYLKETONURIA SOM INNOVATION BIOTECH, S.A. (ES) 2022-05-05 US disclosed
CN-114224834-A Albendazole nano suspension with high bioavailability and preparation method thereof 沈阳伟嘉生物技术有限公司 2022-03-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220133726-A1 TRIAMTERENE OR NOLATREXED FOR USE IN THE TREATMENT OF PHENYLKETONURIA TPMT, MPST, SLC5A6 LMNA 3111/4885TUBB4A 1954/4885TUBB 1700/4885
US-20230181463-A1 OLEOGEL AND OLEOPASTE COMPOSITIONS AND USES THEREOF RAB5IF, OTC, LIPA LMNA 3385/4885TUBB4A 305/4885TUBB 293/4885
US-12257253-B2 Triamterene or nolatrexed for use in the treatment of phenylketonuria TPMT, MPST, SLC5A6 LMNA 3111/4885TUBB4A 1954/4885TUBB 1700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.