Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Albendazole Oxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 known ✓ | Q12809 | 1/20 | 0.50 |
| ▸ | KDR known ✓ | P35968 | 3/20 | 0.44 |
| ▸ | ABL1 known ✓ | P00519 | 1/20 | 0.44 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.43 |
| ▸ | MAPK14 known ✓ | Q16539 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 7/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 6/20 | 0.54 |
| ▸ | TUBB | P07437 | 6/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.54 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.54 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.54 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.54 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.54 |
| ▸ | TUBB2B | Q9BVA1 | 6/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Albendazole Oxide SCHEMBL321413 | 0.99 | LMNA (0.55) | LMNATUBB4ATUBBTUBA3CTUBA1B | |
| Albendazole Oxide SCHEMBL29564405 | 0.99 | LMNA (0.55) | LMNATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL11662850 | 0.90 | LMNA (0.53) | LMNATUBB4ATUBBTUBA3CTUBA1B | |
| Albendazole Oxide SCHEMBL30580728 | 0.90 | LMNA (0.64) | LMNATUBB4ATUBBTUBA3CTUBA1B | |
| Albendazole Oxide SCHEMBL1649240 | 0.90 | LMNA (0.64) | LMNATUBB4ATUBBTUBA3CTUBA1B | |
| Albendazole Oxide SCHEMBL17968582 | 0.90 | LMNA (0.64) | LMNATUBB4ATUBBTUBA3CTUBA1B | |
| Albendazole Oxide SCHEMBL9370388 | 0.89 | LMNA (0.66) | LMNATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL10890981 | 0.87 | NPC1 (0.43) | LMNATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL11266576 | 0.87 | LMNA (0.45) | LMNATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL11213713 | 0.85 | LMNA (0.47) | LMNATUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113648322-A | Ivermectin injection and preparation method thereof | 哈尔滨绿达生动物药业有限公司 | 2021-11-16 | — | — | CN | claimed |
| CN-109431983-A | A kind of compound ivermectin injection and preparation method thereof | 合肥中龙神力动物药业有限公司 | 2019-03-08 | — | — | CN | claimed |
| US-20070053943-A1 | Dimethicone-containing sustained release injection formulation | WANG YUWAN | 2007-03-08 | — | — | US | claimed |
| CN-1519234-A | Preparation of hydrochloric albendazole sulfoxide | 王玉万 | 2004-08-11 | — | — | CN | claimed |
| US-20240000752-A1 | MICROSUSPENSION AGAINST PARASITES AND METHOD FOR OBTAINING SAME | IPANEMA INDUSTRIA DE PRODUTOS VETERINARIOS LTDA (BR) | 2024-01-04 | — | — | US | disclosed |
| EP-4230203-A1 | MICROSUSPENSION AGAINST PARASITES AND METHOD FOR OBTAINING SAME | Ipanema Industria de Produtos Veterinarios Ltda (BR) | 2023-08-23 | — | — | EP | disclosed |
| CN-113648322-A | Ivermectin injection and preparation method thereof | 哈尔滨绿达生动物药业有限公司 | 2021-11-16 | — | — | CN | disclosed |
| CN-113648322-A | Ivermectin injection and preparation method thereof | 哈尔滨绿达生动物药业有限公司 | 2021-11-16 | — | — | CN | disclosed |
| CN-109431983-A | A kind of compound ivermectin injection and preparation method thereof | 合肥中龙神力动物药业有限公司 | 2019-03-08 | — | — | CN | disclosed |
| CN-109431983-A | A kind of compound ivermectin injection and preparation method thereof | 合肥中龙神力动物药业有限公司 | 2019-03-08 | — | — | CN | disclosed |
| US-10052341-B2 | Method for preparing an anthelmintic composition, anthelmintic composition, veterinary treatment method and anthelmintic treatment method | OURO FINO SAUDE ANIMAL PARTICIPACOES SA (BR) | 2018-08-21 | — | — | US | disclosed |
| US-20160303157-A1 | METHOD FOR PREPARING AN ANTHELMINTIC COMPOSITION, ANTHELMINTIC COMPOSITION, VETERINARY TREATMENT METHOD AND ANTHELMINTIC TREATMENT METHOD | OURO FINO SAUDE ANIMAL PARTICIPACOES SA (BR) | 2016-10-20 | — | — | US | disclosed |
| US-7648711-B2 | Dimethicone-containing sustained release injection formulation | WANG YUWAN | 2010-01-19 | — | — | US | disclosed |
| US-20070053943-A1 | Dimethicone-containing sustained release injection formulation | WANG YUWAN | 2007-03-08 | — | — | US | disclosed |
| CN-1522706-A | Preparation of solid dispersoid containing large ring lactone parasite medicine | 王玉万 | 2004-08-25 | — | — | CN | disclosed |
| CN-1518876-A | Bactericide and insecticide in agricultural use containing albendazole sulfoxide and its salt | 王玉万 | 2004-08-11 | — | — | CN | disclosed |
| CN-1519234-A | Preparation of hydrochloric albendazole sulfoxide | 王玉万 | 2004-08-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240000752-A1 | MICROSUSPENSION AGAINST PARASITES AND METHOD FOR OBTAINING SAME | MRPS35, MRPS27, RPS25 | KCNH2 3425/4885KDR 4571/4885ABL1 3324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.