SCHEMBL29564498

SCHEMBL29564498

C[C@@H](O)[C@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)[C@@H](C)O)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ PRMT1 Q99873 1/20 0.63
▸ NPBWR1 P48145 6/20 0.56
▸ IL23R Q5VWK5 9/20 0.52
▸ OPRM1 P35372 2/20 0.52
▸ OPRD1 P41143 2/20 0.52
▸ GHSR Q92847 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29402493 0.98 PRMT1 (0.61) PRMT1NPBWR1IL23ROPRM1OPRD1
SCHEMBL29402413 0.92 PRMT1 (0.67) PRMT1NPBWR1IL23R
SCHEMBL29754403 0.89 GHSR (0.57) PRMT1NPBWR1GHSR
SCHEMBL31541502 0.88 OPRM1 (0.55) PRMT1OPRM1OPRD1GHSR
SCHEMBL31433302 0.86 PRMT1 (0.57) PRMT1NPBWR1OPRM1OPRD1GHSR
SCHEMBL29493326 0.86 PRMT1 (0.63) PRMT1NPBWR1IL23ROPRM1OPRD1
SCHEMBL29361028 0.84 UTS2R (0.55) PRMT1NPBWR1IL23RGHSR
SCHEMBL29524863 0.84 UTS2R (0.55) PRMT1NPBWR1IL23RGHSR
SCHEMBL31252910 0.84 NPBWR1 (0.58) PRMT1NPBWR1GHSR
SCHEMBL29365946 0.83 GHSR (0.64) GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250368736-A1 BISPECIFIC ANTIBODY ONO PHARMACEUTICAL CO., LTD. (JP) 2025-12-04 — — US disclosed
US-12325746-B2 Bispecific antibody ONO PHARMACEUTICAL CO., LTD. (JP) 2025-06-10 — — US disclosed
US-12091461-B2 Bispecific antibody ONO PHARMACEUTICAL CO., LTD. (JP) 2024-09-17 — — US disclosed
US-20240287187-A1 BISPECIFIC ANTIBODY ONO PHARMACEUTICAL CO., LTD. (JP) 2024-08-29 — — US disclosed
US-20220372148-A1 A PHARMACEUTICAL COMPOSITION FOR TREATING HEMATOLOGICAL CANCER ONO PHARMACEUTICAL CO., LTD. (JP) 2022-11-24 — — US disclosed
US-20220281977-A1 BISPECIFIC ANTIBODY ONO PHARMACEUTICAL CO., LTD. (JP) 2022-09-08 — — US disclosed
US-20220185885-A1 BISPECIFIC ANTIBODY ONO PHARMACEUTICAL CO., LTD. (JP) 2022-06-16 — — US disclosed
EP-4008348-A1 BISPECIFIC ANTIBODY ONO Pharmaceutical Co., Ltd. (JP) 2022-06-08 — — EP disclosed
EP-3998081-A1 TREATMENT OF HEMATOLOGIC CANCER WITH PD-1/CD3 DUAL SPECIFICITY PROTEIN Ono Pharmaceutical Co., Ltd. (JP) 2022-05-18 — — EP disclosed
EP-3978015-A1 BISPECIFIC ANTIBODY ONO Pharmaceutical Co., Ltd. (JP) 2022-04-06 — — EP disclosed
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