Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 13/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | LYN | P07948 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | ROS1 | P08922 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24334813 | 1.00 | P2RX7 (0.48) | P2RX7KDRAURKADCLK1PDPK1 | |
| SCHEMBL24334963 | 0.88 | P2RX7 (0.37) | P2RX7KDRAURKADCLK1PDPK1 | |
| SCHEMBL29564933 | 0.88 | P2RX7 (0.37) | P2RX7KDRAURKADCLK1PDPK1 | |
| SCHEMBL29564929 | 0.84 | JAK2 (0.38) | P2RX7KDRAURKADCLK1PDPK1 | |
| SCHEMBL24334966 | 0.83 | P2RX7 (0.43) | P2RX7KDRAURKADCLK1PDPK1 | |
| SCHEMBL24334832 | 0.80 | TLR8 (0.37) | — | |
| SCHEMBL29565448 | 0.80 | TLR8 (0.37) | — | |
| SCHEMBL24334837 | 0.76 | KDR (0.39) | P2RX7KDRAURKADCLK1PDPK1 | |
| SCHEMBL29564816 | 0.76 | KDR (0.39) | P2RX7KDRAURKADCLK1PDPK1 | |
| SCHEMBL24334795 | 0.73 | KCNH2 (0.36) | P2RX7KDRAURKADCLK1PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229065-A1 | OLEFIN POLYMERIZATION CATALYSTS BEARING A 6-AMINO-N-ARYL AZAINDOLE LIGAND | Dow Global Technologies LLC (US) | 2023-08-23 | — | — | EP | disclosed |
| CN-116323626-A | Olefin polymerization catalyst with 6-amino-N-arylazaindole ligands | 陶氏环球技术有限责任公司 | 2023-06-23 | — | — | CN | disclosed |
| WO-2022081685-A1 | OLEFIN POLYMERIZATION CATALYSTS BEARING A 6-AMINO-N-ARYL AZAINDOLE LIGAND | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-04-21 | — | — | WO | disclosed |