Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24334832 | 1.00 | TLR8 (0.37) | TLR8CRHR1MTNR1AMTNR1BCNR2 | |
| SCHEMBL24334990 | 0.85 | SCN5A (0.40) | TLR8MTNR1AMTNR1BGLO1KCNH2 | |
| SCHEMBL29565116 | 0.84 | SOAT1 (0.36) | MTNR1AMTNR1B | |
| SCHEMBL26804220 | 0.84 | SOAT1 (0.36) | MTNR1AMTNR1B | |
| SCHEMBL29564828 | 0.80 | P2RX7 (0.48) | — | |
| SCHEMBL24334813 | 0.80 | P2RX7 (0.48) | — | |
| SCHEMBL24334963 | 0.78 | P2RX7 (0.37) | CRHR1 | |
| SCHEMBL29564933 | 0.78 | P2RX7 (0.37) | CRHR1 | |
| SCHEMBL26805638 | 0.75 | TP53 (0.36) | MTNR1AMTNR1BALDH1A1POLBKMT2A | |
| SCHEMBL29565367 | 0.74 | MTNR1A (0.33) | MTNR1AMTNR1BCNR2GLO1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229065-A1 | OLEFIN POLYMERIZATION CATALYSTS BEARING A 6-AMINO-N-ARYL AZAINDOLE LIGAND | Dow Global Technologies LLC (US) | 2023-08-23 | — | — | EP | disclosed |
| CN-116323626-A | Olefin polymerization catalyst with 6-amino-N-arylazaindole ligands | 陶氏环球技术有限责任公司 | 2023-06-23 | — | — | CN | disclosed |
| WO-2022081685-A1 | OLEFIN POLYMERIZATION CATALYSTS BEARING A 6-AMINO-N-ARYL AZAINDOLE LIGAND | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-04-21 | — | — | WO | disclosed |