Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 4/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | LYN | P07948 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24334963 | 1.00 | P2RX7 (0.37) | P2RX7CYP11B1CYP11B2RAPGEF4KDR | |
| SCHEMBL29564828 | 0.88 | P2RX7 (0.48) | P2RX7KDRAURKADCLK1PDPK1 | |
| SCHEMBL24334813 | 0.88 | P2RX7 (0.48) | P2RX7KDRAURKADCLK1PDPK1 | |
| SCHEMBL26804232 | 0.86 | P2RX7 (0.34) | P2RX7CYP11B1CYP11B2KDRAURKA | |
| SCHEMBL24334795 | 0.85 | KCNH2 (0.36) | P2RX7CYP11B1CYP11B2KDRAURKA | |
| SCHEMBL26804233 | 0.78 | EPHX2 (0.34) | P2RX7CYP11B1CYP11B2TYK2PTK2 | |
| SCHEMBL24334832 | 0.78 | TLR8 (0.37) | CRHR1 | |
| SCHEMBL29565448 | 0.78 | TLR8 (0.37) | CRHR1 | |
| SCHEMBL26805683 | 0.76 | MAPT (0.35) | CYP11B1CYP11B2PTK2 | |
| SCHEMBL24334965 | 0.73 | CYP11B1 (0.39) | P2RX7CYP11B1CYP11B2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229065-A1 | OLEFIN POLYMERIZATION CATALYSTS BEARING A 6-AMINO-N-ARYL AZAINDOLE LIGAND | Dow Global Technologies LLC (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022081685-A1 | OLEFIN POLYMERIZATION CATALYSTS BEARING A 6-AMINO-N-ARYL AZAINDOLE LIGAND | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-04-21 | — | — | WO | disclosed |