Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 4/20 | 0.33 |
| ▸ | EDNRB | P24530 | 3/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9926892 | 1.00 | PDK2 (0.38) | PDK2GPR84ACACAEDNRAEDNRB | |
| SCHEMBL29565411 | 0.95 | PDK2 (0.37) | PDK2GPR84ACACAEDNRAEDNRB | |
| SCHEMBL9926894 | 0.95 | PDK2 (0.37) | PDK2GPR84ACACAEDNRAEDNRB | |
| SCHEMBL9926890 | 0.93 | PDK2 (0.33) | PDK2GPR84EDNRAEDNRBMEN1 | |
| SCHEMBL9926878 | 0.91 | GPR84 (0.35) | PDK2GPR84ACACAPGRMEN1 | |
| SCHEMBL9926893 | 0.90 | GPR84 (0.35) | PDK2GPR84ACACAPGRMEN1 | |
| SCHEMBL15763597 | 0.89 | HTT (0.33) | PDK2GPR84EDNRAEDNRBMEN1 | |
| SCHEMBL16705204 | 0.89 | ESR1 (0.36) | PDK2GPR84ACACAMEN1POLB | |
| SCHEMBL9899249 | 0.87 | ACP1 (0.33) | PDK2GPR84ACACAKDM4EHPGD | |
| SCHEMBL25600768 | 0.86 | GPR84 (0.34) | PDK2GPR84ACACAEDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12111443-B2 | Method for making photochromic contact lenses | ALCON INC. (CH) | 2024-10-08 | — | — | US | claimed |
| US-20240287379-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | ALCON INC. (CH) | 2024-08-29 | — | — | US | claimed |
| CN-115605529-B | Photochromic polydiorganosiloxane vinyl cross-linking agent | 爱尔康公司 | 2024-03-26 | — | — | CN | claimed |
| EP-4313567-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | Alcon Inc. (CH) | 2024-02-07 | — | — | EP | claimed |
| EP-4304843-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | Alcon Inc. (CH) | 2024-01-17 | — | — | EP | claimed |
| EP-4304842-A1 | METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES | Alcon Inc. (CH) | 2024-01-17 | — | — | EP | claimed |
| EP-4158392-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | Alcon Inc. (CH) | 2023-04-05 | — | — | EP | claimed |
| EP-4118134-A1 | PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS | Alcon Inc. (CH) | 2023-01-18 | — | — | EP | claimed |
| CN-115605529-A | Photochromic polydiorganosiloxane ethylene crosslinkers | 爱尔康公司（CH） | 2023-01-13 | — | — | CN | claimed |
| US-20220339895-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | ALCON INC. (CH) | 2022-10-27 | — | — | US | claimed |
| WO-2022208450-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | ALCON INC. (CH) | 2022-10-06 | — | — | WO | claimed |
| WO-2022189941-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | ALCON INC. (CH) | 2022-09-15 | — | — | WO | claimed |
| WO-2022189940-A1 | METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES | ALCON INC. (CH) | 2022-09-15 | — | — | WO | claimed |
| US-20220281193-A1 | METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES | ALCON INC. (CH) | 2022-09-08 | — | — | US | claimed |
| US-20240287379-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | ALCON INC. (CH) | 2024-08-29 | — | — | US | disclosed |
| CN-115605529-B | Photochromic polydiorganosiloxane vinyl cross-linking agent | 爱尔康公司 | 2024-03-26 | — | — | CN | disclosed |
| EP-4313567-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | Alcon Inc. (CH) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022189941-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | ALCON INC. (CH) | 2022-09-15 | — | — | WO | disclosed |
| US-20220281193-A1 | METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES | ALCON INC. (CH) | 2022-09-08 | — | — | US | disclosed |
| WO-2022090967-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | ALCON INC. (CH) | 2022-05-05 | — | — | WO | disclosed |