SCHEMBL29565487

SCHEMBL29565487

COC(=O)c1c2c(c3ccccc3c1O)OC(c1ccccc1)(c1ccc(N(C)C)cc1)C=C2

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.33
ALDH1A1 P00352 6/20 0.33
SMN1; SMN2 Q16637 4/20 0.33
GAA P10253 2/20 0.33
HTT P42858 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
PADI4 Q9UM07 1/20 0.33
MAPT P10636 4/20 0.33
NQO1 P15559 2/20 0.33
RAB9A P51151 2/20 0.33
GABRA1 P14867 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA3 P34903 1/20 0.33
GABRA2 P47869 1/20 0.33
MEN1 O00255 1/20 0.33
RECQL P46063 1/20 0.33
KMT2A Q03164 1/20 0.33
GPR55 Q9Y2T6 1/20 0.33
HPGD P15428 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5159693 1.00 KDM4E (0.33) KDM4EALDH1A1SMN1; SMN2GAAHTT
SCHEMBL5644282 0.92 ALDH1A1 (0.39) KDM4EALDH1A1SMN1; SMN2GAAHTT
SCHEMBL5159521 0.90 SMN1; SMN2 (0.35) KDM4EALDH1A1SMN1; SMN2GAAHTT
SCHEMBL1792470 0.89 MEN1 (0.35) KDM4EALDH1A1SMN1; SMN2GAAHTT
SCHEMBL8978509 0.88 L3MBTL1 (0.40) KDM4EALDH1A1SMN1; SMN2GAAHTT
SCHEMBL29565483 0.88 L3MBTL1 (0.40) KDM4EALDH1A1SMN1; SMN2GAAHTT
SCHEMBL5157934 0.87 GABRA1 (0.33) KDM4EALDH1A1SMN1; SMN2GAAHTT
SCHEMBL8978570 0.86 KDM4E (0.36) KDM4EALDH1A1SMN1; SMN2GAAHTT
SCHEMBL29913570 0.86 KDM4E (0.36) KDM4EALDH1A1SMN1; SMN2GAAHTT
SCHEMBL29565080 0.85 ATM (0.41) KDM4EALDH1A1SMN1; SMN2GAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115605529-B Photochromic polydiorganosiloxane vinyl cross-linking agent 爱尔康公司 2024-03-26 CN claimed
EP-4313567-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2024-02-07 EP claimed
EP-4304842-A1 METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES Alcon Inc. (CH) 2024-01-17 EP claimed
EP-4304843-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2024-01-17 EP claimed
EP-4118134-A1 PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS Alcon Inc. (CH) 2023-01-18 EP claimed
CN-115605529-A Photochromic polydiorganosiloxane ethylene crosslinkers 爱尔康公司(CH) 2023-01-13 CN claimed
WO-2022208450-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-10-06 WO claimed
WO-2022189941-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-09-15 WO claimed
WO-2022189940-A1 METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES ALCON INC. (CH) 2022-09-15 WO claimed
CN-115605529-B Photochromic polydiorganosiloxane vinyl cross-linking agent 爱尔康公司 2024-03-26 CN disclosed
EP-4313567-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2024-02-07 EP disclosed
EP-4304842-A1 METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES Alcon Inc. (CH) 2024-01-17 EP disclosed
EP-4304843-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2024-01-17 EP disclosed
EP-4237232-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2023-09-06 EP disclosed
EP-4118134-A1 PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS Alcon Inc. (CH) 2023-01-18 EP disclosed
CN-115605529-A Photochromic polydiorganosiloxane ethylene crosslinkers 爱尔康公司(CH) 2023-01-13 CN disclosed
WO-2022208450-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-10-06 WO disclosed
WO-2022189941-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-09-15 WO disclosed
WO-2022189940-A1 METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES ALCON INC. (CH) 2022-09-15 WO disclosed
WO-2022090967-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-05-05 WO disclosed