SCHEMBL29367208

SCHEMBL29367208

CC1=CC(C)(C)N([Si](C)(C)C)c2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.53
NPSR1 Q6W5P4 7/20 0.49
TSHR P16473 2/20 0.49
USP2 O75604 1/20 0.49
MAPK1 P28482 1/20 0.49
ALDH1A1 P00352 9/20 0.48
KMT2A Q03164 4/20 0.46
MAPT P10636 3/20 0.46
KDM4E B2RXH2 3/20 0.46
GAA P10253 1/20 0.44
MCOLN3 Q8TDD5 1/20 0.43
MEN1 O00255 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
CYP3A4 P08684 2/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
HPGD P15428 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2393621 0.76 LMNA (0.57) LMNANPSR1TSHRUSP2MAPK1
SCHEMBL23198959 0.75 LMNA (0.53) LMNANPSR1TSHRUSP2MAPK1
SCHEMBL26364047 0.74 LMNA (0.56) LMNANPSR1TSHRUSP2MAPK1
SCHEMBL28226781 0.74 LMNA (0.56) LMNANPSR1TSHRUSP2MAPK1
SCHEMBL2956570 0.74 LMNA (0.56) LMNANPSR1TSHRUSP2MAPK1
SCHEMBL7879104 0.73 LMNA (0.54) LMNANPSR1TSHRUSP2MAPK1
SCHEMBL11589918 0.71 ALDH1A1 (0.57) LMNATSHRMAPK1ALDH1A1KMT2A
SCHEMBL9166728 0.71 LMNA (0.53) LMNANPSR1TSHRUSP2MAPK1
SCHEMBL22129838 0.71 LMNA (0.53) LMNANPSR1TSHRUSP2MAPK1
SCHEMBL29638140 0.71 LMNA (0.53) LMNANPSR1TSHRUSP2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026099687-A1 CROSS-LINKABLE ELASTOMERIC COMPOSITION AND TIRE PIRELLI TYRE S.P.A. (IT) 2026-05-15 WO disclosed
US-12617243-B2 Self-sealing tyre for vehicle wheels PIRELLI TYRE S.P.A. (IT) 2026-05-05 US disclosed
EP-3926007-B1 RUBBER COMPOSITION FOR SUSTAINABLE TIRE HAVING LIGNIN COMPOUNDS HANKOOK TIRE & TECH CO LTD (KR) 2026-02-25 EP disclosed
EP-4461569-B1 A STUDDED TYRE HAVING REDUCED ROAD WEAR NOKIAN RENKAAT OYJ (FI) 2026-02-11 EP disclosed
WO-2025242722-A1 VEHICLE TIRE COMPOSITIONS COMPRISING GRANULATED SILICA AND MICRO PEARL SILICA BRIDGESTONE EUROPE NV/SA (BE) 2025-11-27 WO disclosed
EP-4461566-B1 A STUDDED TYRE HAVING GROOVES NOKIAN RENKAAT OYJ (FI) 2025-11-19 EP disclosed
EP-4644443-A2 SULFUR-CROSSLINKABLE RUBBER COMPOSITION COMPRISING ORGANIC FILLERS AND ORGANOSILANE SunCoal Industries GmbH (DE) 2025-11-05 EP disclosed
EP-4408919-B1 SULFUR-CURABLE RUBBER COMPOSITION CONTAINING ORGANIC FILLERS AND ORGANOSILANE SUNCOAL IND GMBH (DE) 2025-10-29 EP disclosed
EP-4461567-B1 A STUDDED TYRE HAVING SIPES NOKIAN RENKAAT OYJ (FI) 2025-10-29 EP disclosed
EP-4628327-A2 A STUDDED TYRE HAVING REDUCED ROAD WEAR Nokian Renkaat Oyj (FI) 2025-10-08 EP disclosed
US-11597821-B2 Graphene as additive in truck tire tread applications Akron Polymer Solutions, Inc. 2023-03-07 US disclosed
WO-2023025808-A1 PEROXIDE-CROSSLINKABLE RUBBER COMPOSITIONS CONTAINING ORGANIC FILLERS SUNCOAL INDUSTRIES GMBH (DE) 2023-03-02 WO disclosed
US-20230031239-A1 GRAPHENE AS ADDITIVE IN TRUCK TIRE TREAD APPLICATIONS Akron Polymer Solutions, Inc. 2023-02-02 US disclosed
WO-2023288270-A1 GRAPHENE AS ADDITIVE IN TRUCK TIRE TREAD APPLICATIONS Akron Polymer Solutions, Inc. (US) 2023-01-19 WO disclosed
WO-2022243486-A1 SURFACE-MODIFIED ORGANIC FILLERS AND RUBBER COMPOSITIONS CONTAINING SAME SUNCOAL INDUSTRIES GMBH (DE) 2022-11-24 WO disclosed
WO-2022243487-A1 ORGANOSILANE-MODIFIED ORGANIC FILLERS AND RUBBER COMPOSITIONS CONTAINING SAID FILLERS KOEHLER INNOVATION & TECHNOLOGY GMBH (DE) 2022-11-24 WO disclosed
WO-2022112994-A1 PROCESS FOR PREPARING AN ELASTOMERIC COMPOSITION AND TYRES COMPRISING THE SAME PIRELLI TYRE S.P.A. (IT) 2022-06-02 WO disclosed
WO-2022101926-A1 UN-MODIFIED FULLER'S EARTH NANOCLAY RUBBER NANOCOMPOSITE FOR TYRE AND METHOD THEREOF TVS SRICHAKRA LIMITED (IN) 2022-05-19 WO disclosed
CN-114315713-A Preparation method of low primary amine TMQ (tetramethylammonium terephthalate) antioxidant 中石化南京化工研究院有限公司 2022-04-12 CN disclosed
CN-104558860-B Polymer resin composition for preparing insulation material with enhanced thermal stability 尼克桑斯公司 2022-02-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617243-B2 Self-sealing tyre for vehicle wheels VIL1, TRHDE, POT1 LMNA 114/4885NPSR1 4210/4885TSHR 700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.