Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | RXRG | P48443 | 1/20 | 0.48 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.47 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16516853 | 1.00 | FFAR1 (0.50) | FFAR1FFAR4RXRARXRBRXRG | |
| SCHEMBL7792665 | 0.92 | FFAR1 (0.51) | FFAR1FFAR4RXRARXRBRXRG | |
| SCHEMBL17911599 | 0.83 | FFAR1 (0.48) | FFAR1FFAR4RXRARXRBRXRG | |
| SCHEMBL7796119 | 0.80 | GAA (0.64) | RXRARXRBRXRGRARARARB | |
| SCHEMBL7794917 | 0.80 | FFAR1 (0.48) | FFAR1FFAR4RXRARXRBRXRG | |
| SCHEMBL17911568 | 0.79 | FFAR1 (0.55) | FFAR1FFAR4RXRARXRBRXRG | |
| SCHEMBL3493151 | 0.79 | S1PR1 (0.59) | FFAR1FFAR4RXRARXRBRXRG | |
| SCHEMBL8765888 | 0.78 | RARA (0.73) | FFAR1FFAR4RXRARXRBRXRG | |
| SCHEMBL8765882 | 0.78 | RARA (0.73) | FFAR1FFAR4RXRARXRBRXRG | |
| SCHEMBL7792671 | 0.78 | FFAR1 (0.47) | FFAR1FFAR4RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3044216-B1 | NOVEL AND SPECIFIC INHIBITORS OF CYTOCHROME P450 26 RETINOIC ACID HYDROXYLASE | UNIV WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2022-02-23 | — | — | EP | claimed |