SCHEMBL7792665

SCHEMBL7792665

COc1ccc(CCC(=O)O)cc1C(C)(C)C

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 8/20 0.51
FFAR4 Q5NUL3 6/20 0.51
PPARA Q07869 2/20 0.50
FFAR2 O15552 1/20 0.49
PPARD Q03181 1/20 0.49
RXRA P19793 1/20 0.49
RXRB P28702 1/20 0.49
RXRG P48443 1/20 0.49
RARA P10276 2/20 0.47
RARB P10826 2/20 0.47
RARG P13631 2/20 0.47
S1PR1 P21453 1/20 0.47
S1PR5 Q9H228 1/20 0.47
ALOX5 P09917 1/20 0.46
OR51E2 Q9H255 1/20 0.46
FABP4 P15090 1/20 0.46
GAA P10253 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16516853 0.92 FFAR1 (0.50) FFAR1FFAR4PPARAFFAR2PPARD
SCHEMBL29567262 0.92 FFAR1 (0.50) FFAR1FFAR4PPARAFFAR2PPARD
SCHEMBL7794917 0.87 FFAR1 (0.48) FFAR1FFAR4PPARAFFAR2PPARD
SCHEMBL3493151 0.87 S1PR1 (0.59) FFAR1FFAR4PPARAFFAR2PPARD
SCHEMBL7792671 0.86 FFAR1 (0.47) FFAR1FFAR4PPARAFFAR2PPARD
SCHEMBL7796630 0.85 RXRA (0.49) FFAR1FFAR4RXRARXRBRXRG
SCHEMBL9162014 0.85 RXRA (0.47) FFAR1FFAR4RXRARXRBRXRG
SCHEMBL17911599 0.85 FFAR1 (0.48) FFAR1FFAR4PPARAPPARDRXRA
SCHEMBL7796119 0.84 GAA (0.64) RXRARXRBRXRGRARARARB
SCHEMBL347209 0.82 FFAR4 (0.61) FFAR1FFAR4ALOX5OR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed