SCHEMBL7794917

SCHEMBL7794917

CCC(C)(C)c1cc(CCC(=O)O)ccc1OC

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 9/20 0.48
FFAR4 Q5NUL3 7/20 0.48
PPARA Q07869 2/20 0.47
FFAR2 O15552 1/20 0.46
PPARD Q03181 1/20 0.46
S1PR1 P21453 1/20 0.44
S1PR5 Q9H228 1/20 0.44
FABP4 P15090 1/20 0.43
ALOX5 P09917 1/20 0.43
OR51E2 Q9H255 1/20 0.43
RXRA P19793 1/20 0.43
RXRB P28702 1/20 0.43
RXRG P48443 1/20 0.43
PLA2G4A P47712 1/20 0.42
GAA P10253 1/20 0.42
CYP19A1 P11511 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7792671 0.88 FFAR1 (0.47) FFAR1FFAR4PPARAFFAR2PPARD
SCHEMBL7792665 0.87 FFAR1 (0.51) FFAR1FFAR4PPARAFFAR2PPARD
SCHEMBL7792674 0.86 LTA4H (0.47) FFAR1FFAR4PPARAFFAR2PPARD
SCHEMBL7796102 0.86 GAA (0.59) FABP4RXRARXRBRXRGGAA
SCHEMBL3493151 0.83 S1PR1 (0.59) FFAR1FFAR4PPARAFFAR2PPARD
SCHEMBL6566990 0.82 TSHR (0.41) CYP19A1
SCHEMBL2491545 0.81 IAPP (0.46) FFAR1FFAR4ALOX5OR51E2RXRA
SCHEMBL6568739 0.80 TNKS2 (0.45) PPARAALOX5
SCHEMBL16516853 0.80 FFAR1 (0.50) FFAR1FFAR4PPARAFFAR2PPARD
SCHEMBL29567262 0.80 FFAR1 (0.50) FFAR1FFAR4PPARAFFAR2PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed