SCHEMBL29567368

SCHEMBL29567368

Nc1ccn(C2CC(OP(=O)(O)OCC3OC(n4cnc5c(N)ncnc54)CC3OP(=O)(O)OCC3OC(n4cnc5c(=O)[nH]c(N)nc54)CC3O)C(CO)O2)c(=O)n1

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ P2RY2 P41231 3/20 0.56
▸ P2RY4 P51582 3/20 0.56
▸ P2RY6 Q15077 3/20 0.56
▸ POLB P06746 3/20 0.56
▸ F2 P00734 1/20 0.54
▸ TERT O14746 2/20 0.52
▸ DTYMK P23919 4/20 0.49
▸ ENPP1 P22413 2/20 0.49
▸ P2RY1 P47900 1/20 0.49
▸ FUT5 Q11128 1/20 0.47
▸ RNASEL Q05823 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31276800 1.00 P2RY2 (0.56) P2RY2P2RY4P2RY6POLBF2
SCHEMBL29551577 1.00 P2RY2 (0.56) P2RY2P2RY4P2RY6POLBF2
SCHEMBL23071689 0.96 P2RY2 (0.53) P2RY2P2RY4P2RY6POLBF2
SCHEMBL23071682 0.96 P2RY2 (0.53) P2RY2P2RY4P2RY6POLBF2
SCHEMBL23071694 0.96 P2RY2 (0.53) P2RY2P2RY4P2RY6POLBF2
SCHEMBL30839331 0.96 P2RY2 (0.57) P2RY2P2RY4P2RY6POLBF2
SCHEMBL29551697 0.95 P2RY2 (0.61) P2RY2P2RY4P2RY6POLBF2
SCHEMBL29365163 0.95 P2RY2 (0.61) P2RY2P2RY4P2RY6POLBF2
SCHEMBL8614074 0.94 P2RY2 (0.62) P2RY2P2RY4P2RY6POLBF2
SCHEMBL8613676 0.94 P2RY2 (0.62) P2RY2P2RY4P2RY6POLBF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12497609-B2 Protospacer adjacent motif sequence and method for modifying target nucleic acid in genome of cell by using same YONSEI UNIVERSITY BIOHEALTH TECHNOLOGY HOLDINGS. INC. (KR) 2025-12-16 — — US claimed
US-20250019739-A1 EXONUCLEASE-COUPLED REAL-TIME ENDONUCLEASE ACTIVITY ASSAY CARIBOU BIOSCIENCES, INC. (US) 2025-01-16 — — US claimed
CN-114555803-B Novel prosomain sequence adjacent motif sequences and methods of using the same for modifying target nucleic acids in cellular genomes 延世大学校产学协力团 2024-11-29 — — CN claimed
US-20240384268-A1 Oligonucleotides Hudson Institute of Medical Research (AU) 2024-11-21 — — US claimed
EP-4423502-A1 EXONUCLEASE-COUPLED REAL-TIME ENDONUCLEASE ACTIVITY ASSAY Caribou Biosciences, Inc. (US) 2024-09-04 — — EP claimed
WO-2024099575-A1 ARTIFICIAL NUCLEIC ACIDS FOR SITE-DIRECTED EDITING OF A TARGET RNA EBERHARD KARLS UNIVERSITÄT TÜBINGEN (DE) 2024-05-16 — — WO claimed
CN-117999481-A Exonuclease coupled real-time endonuclease activity assay 卡里布生物科学公司 2024-05-07 — — CN claimed
EP-4320237-A1 OLIGONUCLEOTIDES Hudson Institute of Medical Research (AU) 2024-02-14 — — EP claimed
CN-117043340-A Oligonucleotides 哈德森医学研究所 2023-11-10 — — CN claimed
WO-2023097268-A2 EXTRACELLULAR VESICLES COMPRISING NON-NATURALLY OCCURRING MODULAR RNA HAIRPINS AND USES THEREOF MANTRA BIO, INC. (US) 2023-06-01 — — WO claimed
WO-2023075154-A1 METHOD FOR INACTIVATING GENE OF PORCINE ENDOGENOUS RETROVIRUS AND COMPOSITION THEREOF 주식회사 툴젠 2023-05-04 — — WO claimed
WO-2023076857-A1 EXONUCLEASE-COUPLED REAL-TIME ENDONUCLEASE ACTIVITY ASSAY CARIBOU BIOSCIENCES, INC. (US) 2023-05-04 — — WO claimed
US-20230074760-A1 NOVEL PROTOSPACER ADJACENT MOTIF SEQUENCE AND METHOD FOR MODIFYING TARGET NUCLEIC ACID IN GENOME OF CELL BY USING SAME INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2023-03-09 — — US claimed
WO-2022213153-A1 OLIGONUCLEOTIDES Hudson Institute of Medical Research (AU) 2022-10-13 — — WO claimed
CN-114555803-A Prespacer sequence adjacent motif sequence and method for modifying target nucleic acid in cell genome by using the same 延世大学校产学协力团 2022-05-27 — — CN claimed
US-20260109985-A1 THERAPY BY TRANS-SPLICING OF OPA1 PRE-MESSENGER RNAS FOR THE TREATMENT OF DISEASES ASSOCIATED WITH OPA1 GENE MUTATIONS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2026-04-23 — — US disclosed
EP-3727435-B1 BIVALENT NUCLEIC ACID LIGANDS AND USES THEREFOR UNIV CARNEGIE MELLON (US) 2026-02-18 — — EP disclosed
WO-2022213153-A1 OLIGONUCLEOTIDES Hudson Institute of Medical Research (AU) 2022-10-13 — — WO disclosed
CN-115171783-A Method and device for directed evolution of enzyme 上海合全药业股份有限公司 2022-10-11 — — CN disclosed
CN-114555803-A Prespacer sequence adjacent motif sequence and method for modifying target nucleic acid in cell genome by using the same 延世大学校产学协力团 2022-05-27 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109985-A1 THERAPY BY TRANS-SPLICING OF OPA1 PRE-MESSENGER RNAS FOR THE TREATMENT OF DISEASES ASSOCIATED WITH OPA1 GENE MUTATIONS OPA1, UPF1, POLRMT P2RY2 4211/4885P2RY4 4679/4885P2RY6 4730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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