Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP2C18 | P33260 | 2/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4872919 | 0.79 | MAPT (0.45) | ALDH1A1MAPTATMCYP2C9CYP2C19 | |
| SCHEMBL5732531 | 0.75 | ALDH1A1 (0.42) | ALDH1A1MAPTATMCYP2C9CYP2C19 | |
| SCHEMBL23401442 | 0.74 | RAB9A (0.40) | ALDH1A1MAPTCYP2C9CYP2C19NPSR1 | |
| SCHEMBL5266895 | 0.73 | CYP2C9 (0.44) | ALDH1A1CYP2C9CYP2C19CYP2C18CYP2C8 | |
| SCHEMBL17788545 | 0.71 | CYP1A2 (0.45) | KDM5AKDM5BALDH1A1MAPTCYP2C9 | |
| SCHEMBL23401516 | 0.71 | ALDH1A1 (0.44) | ALDH1A1MAPTATMCYP2C9CYP2C19 | |
| SCHEMBL23130273 | 0.70 | CYP2C9 (0.49) | KDM5AKDM5BALDH1A1MAPTATM | |
| SCHEMBL23402558 | 0.70 | ALDH1A1 (0.42) | ALDH1A1MAPTNPSR1RAB9ANPC1 | |
| SCHEMBL23398771 | 0.70 | RAB9A (0.41) | ALDH1A1MAPTNPSR1RAB9ANPC1 | |
| SCHEMBL27721618 | 0.70 | RAB9A (0.50) | ALDH1A1MAPTCYP2C9CYP2C19NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767674-B2 | Kinase inhibitors | ELI LILLY AND COMPANY (US) | 2010-08-03 | — | — | US | disclosed |
| US-20080306068-A1 | Suppression cytokines, tumor necrosis factor | ELI LILLY AND COMPANY (US) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306068-A1 | Suppression cytokines, tumor necrosis factor | TNF, TNFRSF1A, IL2 | KDM5A 3017/4885KDM5B 2786/4885ALDH1A1 2315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.