Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 6/20 | 0.35 |
| ▸ | JAK3 | P52333 | 5/20 | 0.35 |
| ▸ | KDM4A | O75164 | 4/20 | 0.35 |
| ▸ | KDM4B | O94953 | 4/20 | 0.35 |
| ▸ | KDM5C | P41229 | 4/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 3/20 | 0.34 |
| ▸ | JAK1 | P23458 | 4/20 | 0.34 |
| ▸ | TYK2 | P29597 | 3/20 | 0.33 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29567173 | 0.87 | LRRK2 (0.43) | KDM4AKDM4BKDM5CKDM5BGRM4 | |
| SCHEMBL29480516 | 0.87 | KDM4A (0.36) | KDM4AKDM4BKDM5CKDM5BGRM4 | |
| SCHEMBL22736007 | 0.87 | LRRK2 (0.43) | KDM4AKDM4BKDM5CKDM5BGRM4 | |
| SCHEMBL22736015 | 0.81 | JAK1 (0.34) | JAK2JAK3KDM4AKDM4BKDM5C | |
| SCHEMBL29480520 | 0.81 | JAK1 (0.34) | JAK2JAK3KDM4AKDM4BKDM5C | |
| SCHEMBL22736280 | 0.80 | GRM4 (0.38) | JAK2KDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL29480555 | 0.80 | GRM4 (0.38) | JAK2KDM4AKDM4BKDM5CKDM5B | |
| SCHEMBL29567573 | 0.78 | JAK2 (0.34) | JAK2JAK1GRM4 | |
| SCHEMBL22716894 | 0.78 | JAK2 (0.34) | JAK2JAK1GRM4 | |
| SCHEMBL22736278 | 0.78 | GRM4 (0.35) | JAK2JAK3KDM4AKDM4BKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12516056-B2 | Compounds for inhibition of janus kinase 1 | MANKIND PHARMA LTD. (IN) | 2026-01-06 | — | — | US | claimed |
| EP-3976612-A1 | NOVEL COMPOUNDS FOR INHIBITION OF JANUS KINASE 1 | MANKIND PHARMA LTD (IN) | 2022-04-06 | — | — | EP | claimed |
| US-12516056-B2 | Compounds for inhibition of janus kinase 1 | MANKIND PHARMA LTD. (IN) | 2026-01-06 | — | — | US | disclosed |
| US-20220235046-A1 | NOVEL COMPOUNDS FOR INHIBITION OF JANUS KINASE 1 | MANKIND PHARMA LTD. (IN) | 2022-07-28 | — | — | US | disclosed |
| EP-3976612-A1 | NOVEL COMPOUNDS FOR INHIBITION OF JANUS KINASE 1 | MANKIND PHARMA LTD (IN) | 2022-04-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220235046-A1 | NOVEL COMPOUNDS FOR INHIBITION OF JANUS KINASE 1 | JAK1, JAK2, JAK3 | JAK2 2/4885JAK3 3/4885KDM4A 984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.