SCHEMBL29568321

SCHEMBL29568321

Cc1ccc2c(c1)C(=O)NC2=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPOX P50336 1/20 0.56
ROS1 P08922 1/20 0.55
CDK5 Q00535 1/20 0.55
ACVR1 Q04771 1/20 0.55
LRRK2 Q5S007 1/20 0.55
EGFR P00533 1/20 0.55
KMT2A Q03164 3/20 0.53
MEN1 O00255 2/20 0.53
MAOA P21397 3/20 0.52
MAOB P27338 3/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA4 P22748 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
ELANE P08246 1/20 0.50
GSK3B P49841 1/20 0.50
TDP1 Q9NUW8 2/20 0.48
CYP3A4 P08684 1/20 0.48
CASP3 P42574 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL145900 1.00 PPOX (0.56) PPOXROS1CDK5ACVR1LRRK2
Hydrogen Sulfide SCHEMBL9815133 0.98 PPOX (0.54) PPOXROS1CDK5ACVR1LRRK2
SCHEMBL23945611 0.91 MAOA (0.59) PPOXROS1CDK5ACVR1LRRK2
SCHEMBL14413906 0.83 ROS1 (0.49) PPOXROS1CDK5ACVR1LRRK2
SCHEMBL21573560 0.83 ROS1 (0.49) PPOXROS1CDK5ACVR1LRRK2
SCHEMBL28385067 0.83 ROS1 (0.49) PPOXROS1CDK5ACVR1LRRK2
SCHEMBL11669965 0.83 ROS1 (0.49) PPOXROS1CDK5ACVR1LRRK2
SCHEMBL15108881 0.78 MAPT (0.47) PPOXROS1CDK5ACVR1LRRK2
SCHEMBL23601550 0.78 FYN (0.58) PPOXROS1CDK5ACVR1LRRK2
SCHEMBL257975 0.78 MAOA (0.72) EGFRKMT2AMEN1MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4206205-B1 PREPARATION METHOD FOR PYRROLOPYRIMIDINE COMPOUND PRIMEGENE BEIJING CO LTD (CN) 2026-03-04 EP claimed
EP-4697457-A1 CARBON DIOXIDE ADSORPTION BATTERY, CHARGE/DISCHARGE DEVICE, AND CARBON DIOXIDE CONCENTRATION DEVICE Kuraray Co., Ltd. (JP) 2026-02-18 EP disclosed
EP-4590674-A1 NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF Sironax Ltd (KY) 2025-07-30 EP disclosed
WO-2024232337-A1 CARBON DIOXIDE ADSORPTION BATTERY, CHARGE/DISCHARGE DEVICE, AND CARBON DIOXIDE CONCENTRATION DEVICE 株式会社クラレ 2024-11-14 WO disclosed
CN-116535344-B Phthalimide preparation method of class compound 华南理工大学 2024-10-01 CN disclosed
CN-118580250-A Method for synthesizing oxygen bridge full-carbon seven-membered ring compound 华东理工大学 2024-09-03 CN disclosed
CN-116535344-A Preparation method of phthalimide compound 华南理工大学 2023-08-04 CN disclosed
CN-114349679-A Preparation method of biaryl axial chiral compound 五邑大学 2022-04-15 CN disclosed