Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.58 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.58 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.58 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.55 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | PPOX | P50336 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | WEE1 | P30291 | 1/20 | 0.41 |
| ▸ | ROS1 | P08922 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319902 | 0.82 | PPOX (0.60) | GSK3BPPOXTDP2MAOAMAOB | |
| SCHEMBL8962219 | 0.82 | PPOX (0.60) | GSK3BPPOXTDP2MAOAMAOB | |
| SCHEMBL1276074 | 0.81 | TDP2 (0.61) | CLK4DYRK1BPARP10PARP11KMT2A | |
| SCHEMBL17991477 | 0.81 | MAPK1 (0.53) | KMT2AMAPT | |
| Phthalimide SCHEMBL2261244 | 0.79 | GSK3B (0.65) | DYRK1BKMT2AGSK3BGSK3AMAOA | |
| SCHEMBL145900 | 0.78 | PPOX (0.56) | PARP10PARP11KMT2AGSK3BPPOX | |
| SCHEMBL29568321 | 0.78 | PPOX (0.56) | PARP10PARP11KMT2AGSK3BPPOX | |
| SCHEMBL24721527 | 0.78 | MAOA (0.49) | GSK3BPPOXTDP2CHEK1MAOA | |
| SCHEMBL24721730 | 0.78 | RXRA (0.50) | KMT2AGSK3BPPOXTDP2CHEK1 | |
| SCHEMBL28398276 | 0.77 | FYN (0.37) | FYNCLK4DYRK1BPARP10PARP11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |