Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL149402 | 0.85 | TSHR (0.40) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Acrylic Acid SCHEMBL27531090 | 0.84 | LMNA (0.62) | LMNAALDH1A1TSHRALOX15HSD17B10 | |
| Acrylamide SCHEMBL23607548 | 0.83 | ALDH1A1 (0.52) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Acrylic Acid SCHEMBL28130031 | 0.81 | — | — | |
| Acrylic Acid SCHEMBL28300132 | 0.81 | LMNA (0.59) | LMNAALDH1A1TSHRALOX15HSD17B10 | |
| Acrylic Acid SCHEMBL28549354 | 0.81 | LMNA (0.40) | LMNAALDH1A1ALOX15HSD17B10 | |
| Acrylic Acid SCHEMBL151092 | 0.79 | LMNA (0.56) | LMNAALDH1A1TSHRALOX15HSD17B10 | |
| Acrylic Acid SCHEMBL28958317 | 0.78 | LMNA (0.62) | LMNAALDH1A1TSHRALOX15HSD17B10 | |
| Acrylamide SCHEMBL23607541 | 0.78 | ALDH1A1 (0.52) | ALDH1A1TSHRHPGD | |
| Acrylamide SCHEMBL23607544 | 0.78 | ALDH1A1 (0.52) | ALDH1A1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114351460-B | Fiber material with antibacterial function, preparation method thereof and fiber product thereof | 广州弘海材料科技有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-114351460-A | Fiber material with antibacterial function, preparation method thereof and fiber product thereof | 广州弘海材料科技有限公司 | 2022-04-15 | — | — | CN | disclosed |