SCHEMBL29568971

CC[C@H](C)[C@H](N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O)[C@@H](C)CC)C(C)C

nearest known ligand 0.60

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	REN	P00797	10/20	0.60

▸	LNPEP	Q9UIQ6	5/20	0.56

▸	ANPEP	P15144	2/20	0.56

▸	AGTR1	P30556	1/20	0.55

▸	AGTR2	P50052	1/20	0.55

▸	F2	P00734	2/20	0.53

▸	NTSR2	O95665	1/20	0.52

▸	NTSR1	P30989	1/20	0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29568453	0.94	REN (0.62)	RENAGTR1AGTR2F2NTSR2
SCHEMBL29448209	0.94	REN (0.66)	RENLNPEPANPEPAGTR1AGTR2
SCHEMBL29568973	0.94	REN (0.55)	RENLNPEPANPEPF2NTSR2
SCHEMBL9010597	0.92	LNPEP (0.64)	RENLNPEPANPEPAGTR1AGTR2
SCHEMBL9010601	0.92	LNPEP (0.64)	RENLNPEPANPEPAGTR1AGTR2
SCHEMBL29569038	0.91	NTSR2 (0.61)	RENAGTR1AGTR2NTSR2NTSR1
SCHEMBL29569348	0.91	NTSR1 (0.59)	RENAGTR1AGTR2F2NTSR2
SCHEMBL29559228	0.90	LNPEP (0.55)	RENLNPEPANPEPAGTR1AGTR2
Angiotensin Iv SCHEMBL4322236	0.90	LNPEP (0.68)	RENLNPEPANPEPAGTR1AGTR2
Angiotensin Iv SCHEMBL4322224	0.90	LNPEP (0.68)	RENLNPEPANPEPAGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3320923-B1	FLUORESCENT IMAGING AGENTS	VISEN MEDICAL INC (US)	2022-04-06	—	—	EP	claimed
EP-3320923-B1	FLUORESCENT IMAGING AGENTS	VISEN MEDICAL INC (US)	2022-04-06	—	—	EP	disclosed