Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 7/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | PPARG | P37231 | 2/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.57 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.57 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.57 |
| ▸ | ALB | P02768 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10674228 | 0.90 | TDP1 (0.59) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10674221 | 0.90 | TDP1 (0.59) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL11155800 | 0.90 | TDP1 (0.59) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL11010391 | 0.87 | NR1I2 (0.76) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10606264 | 0.86 | TDP1 (0.72) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10606259 | 0.86 | TDP1 (0.72) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL11009334 | 0.86 | NR1I2 (0.57) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL11009331 | 0.86 | NR1I2 (0.57) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10671707 | 0.85 | TDP1 (0.49) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10671700 | 0.85 | TDP1 (0.49) | NR1I2HTR2CMAPTPPARGSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250375505-A1 | COMPOSITIONS AND METHODS FOR MODIFYING BILE ACIDS TO REGULATE LIPID AND STEROID METABOLISM | UNIV CALIFORNIA (US) | 2025-12-11 | — | — | US | disclosed |
| US-20250313905-A1 | METHODS AND COMPOSITIONS FOR IMPROVED PSYCHOLOGICAL AND RESILIENCE MEASURES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2025-10-09 | — | — | US | disclosed |
| US-12364717-B2 | Compositions and methods for inhibiting seizures | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-07-22 | — | — | US | disclosed |
| US-12292445-B2 | Methods of selecting subjects for treatment with metabolomic modulators | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-05-06 | — | — | US | disclosed |
| EP-4525896-A1 | METHODS AND COMPOSITIONS FOR IMPROVED PSYCHOLOGICAL AND RESILIENCE MEASURES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-03-26 | — | — | EP | disclosed |
| WO-2025038777-A2 | PROBIOTICS AND METHODS TO REDUCE APPETITE | BLOOM SCIENCE, INC. (US) | 2025-02-20 | — | — | WO | disclosed |
| EP-4509174-A2 | COMPOSITIONS AND METHODS FOR PROMOTING SKIN HEALTH | The Regents of the University of California (US) | 2025-02-19 | — | — | EP | disclosed |
| US-20250025516-A1 | COMPOSITIONS AND METHODS FOR INHIBITING SEIZURES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2025-01-23 | — | — | US | disclosed |
| CN-119033822-A | Compositions and methods for inhibiting seizures | 加利福尼亚大学董事会 | 2024-11-29 | — | — | CN | disclosed |
| WO-2024233640-A1 | COMPOSITIONS AND METHODS FOR INHIBITING SEIZURES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-11-14 | — | — | WO | disclosed |
| US-20230310515-A1 | COMPOSITIONS AND METHODS FOR TREATING SKIN INFECTIONS AND OTHER DISEASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-10-05 | — | — | US | disclosed |
| WO-2023114180-A1 | COMPOSITIONS AND METHODS FOR MODIFYING BILE ACIDS TO REGULATE LIPID AND STEROID METABOLISM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023102170-A1 | COMPOSITIONS AND METHODS FOR INHIBITING SEIZURES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-08 | — | — | WO | disclosed |
| WO-2022243703-A1 | METHOD OF PROGNOSIS | PLAQUETEC LTD (GB) | 2022-11-24 | — | — | WO | disclosed |
| US-20220257646-A1 | COMPOSITIONS AND METHODS FOR TREATING SKIN CONDITIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-08-18 | — | — | US | disclosed |
| US-20220218762-A1 | COMPOSITIONS AND METHODS FOR MODULATING COGNITIVE BEHAVIOR | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-07-14 | — | — | US | disclosed |
| US-20220184144-A1 | COMPOSITIONS AND METHODS FOR INHIBITING SEIZURES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-06-16 | — | — | US | disclosed |
| EP-4003381-A1 | COMPOSITIONS AND METHODS FOR TREATING SKIN INFECTIONS AND OTHER DISEASES | The Regents of the University of California (US) | 2022-06-01 | — | — | EP | disclosed |
| EP-3999076-A1 | COMPOSITIONS AND METHODS FOR TREATING SKIN CONDITIONS | The Regents of the University of California (US) | 2022-05-25 | — | — | EP | disclosed |
| EP-3976026-A2 | COMPOSITIONS AND METHODS FOR MODULATING COGNITIVE BEHAVIOR | The Regents of the University of California (US) | 2022-04-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250375505-A1 | COMPOSITIONS AND METHODS FOR MODIFYING BILE ACIDS TO REGULATE LIPID AND STEROID METABOLISM | CYP27A1, LIPC, CYP46A1 | NR1I2 667/4885HTR2C 4394/4885MAPT 1772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.