Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | NOS1 | P29475 | 1/20 | 0.56 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25344191 | 1.00 | TBXAS1 (0.64) | TBXAS1ALDH1A1KDM4EKMT2ANPSR1 | |
| SCHEMBL4131855 | 0.85 | TBXAS1 (0.70) | TBXAS1ALDH1A1KDM4EKMT2ANOS1 | |
| SCHEMBL12382 | 0.80 | KMT2A (0.87) | TBXAS1ALDH1A1KDM4EKMT2ANPSR1 | |
| SCHEMBL1928520 | 0.80 | TBXAS1 (0.68) | TBXAS1ALDH1A1KDM4EKMT2ANPSR1 | |
| SCHEMBL3581172 | 0.80 | ALDH1A1 (0.85) | TBXAS1ALDH1A1KDM4EKMT2ANPSR1 | |
| SCHEMBL9451380 | 0.80 | TBXAS1 (0.68) | TBXAS1ALDH1A1KDM4EKMT2ANPSR1 | |
| SCHEMBL10370478 | 0.78 | TBXAS1 (1.00) | TBXAS1ALDH1A1KDM4EKMT2ANOS1 | |
| SCHEMBL8995364 | 0.78 | QPCT (0.69) | TBXAS1KDM4EKMT2ANOS1 | |
| Hydrochloric Acid SCHEMBL9996050 | 0.77 | TBXAS1 (0.97) | TBXAS1ALDH1A1KDM4EKMT2ANOS1 | |
| SCHEMBL7472307 | 0.77 | TBXAS1 (0.61) | TBXAS1ALDH1A1KDM4EKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116940562-A | Acetamido-phenylbenzamide derivatives and methods of use thereof | 希华医药有限公司 | 2023-10-24 | — | — | CN | disclosed |
| EP-4225745-A1 | ACETAMIDO-PHENYLBENZAMIDE DERIVATIVES AND METHODS OF USING THE SAME | Athenex, Inc. (US) | 2023-08-16 | — | — | EP | disclosed |
| WO-2022076662-A1 | ACETAMIDO-PHENYLBENZAMIDE DERIVATIVES AND METHODS OF USING THE SAME | ATHENEX, INC. (US) | 2022-04-14 | — | — | WO | disclosed |