Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | PDE2A | O00408 | 7/20 | 0.42 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7599544 | 0.81 | CES2 (0.47) | CES2PDE2APTPN5IDO1TDO2 | |
| SCHEMBL2954138 | 0.79 | CES2 (0.46) | CES2PDE2APTPN5IDO1TDO2 | |
| SCHEMBL2964976 | 0.79 | CES2 (0.50) | CES2PDE2APTPN5IDO1TDO2 | |
| SCHEMBL6390437 | 0.79 | IDO1 (0.38) | CES2IDO1TSHRGLAPOLB | |
| SCHEMBL12868145 | 0.79 | PDE2A (0.46) | CES2PDE2APTPN5HTR2ASLC6A4 | |
| SCHEMBL6061078 | 0.77 | CES2 (0.56) | CES2PDE2APTPN5GPR3TSHR | |
| SCHEMBL23675536 | 0.76 | PDE2A (0.61) | CES2PDE2AHTR2A | |
| SCHEMBL14121399 | 0.76 | PDE2A (0.43) | CES2PDE2AIDO1TDO2TSHR | |
| SCHEMBL22717245 | 0.76 | P2RX7 (0.47) | CES2PDE2APTPN5IDO1TDO2 | |
| SCHEMBL22717043 | 0.76 | PDE2A (0.61) | CES2PDE2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8298830-B2 | Organic materials able to detect analytes | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-10-30 | — | — | US | disclosed |
| US-20100310424-A1 | ORGANIC MATERIALS ABLE TO DETECT ANALYTES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-12-09 | — | — | US | disclosed |
| US-7759127-B2 | Organic materials able to detect analytes | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-07-20 | — | — | US | disclosed |
| US-7700366-B2 | Fluorescent, semi-conductive polymers, and devices comprising them | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-04-20 | — | — | US | disclosed |
| US-20060073607-A1 | Organic materials able to detect analytes | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-04-06 | — | — | US | disclosed |
| US-20050196775-A1 | Fluorescent, semi-conductive polymers, and devices comprising them | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2005-09-08 | — | — | US | disclosed |
| WO-2005073338-A2 | FLUORESCENT, SEMI-CONDUCTIVE POLYMERS, AND DEVICES COMPRISING THEM | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2005-08-11 | — | — | WO | disclosed |