Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.50 |
| ▸ | PDE2A | O00408 | 6/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.34 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.34 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.34 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22717043 | 0.84 | PDE2A (0.61) | CES2PDE2ACYP3A4CYP2D6ORAI1 | |
| SCHEMBL23675536 | 0.84 | PDE2A (0.61) | CES2PDE2ACYP3A4CYP2D6ORAI1 | |
| SCHEMBL19696153 | 0.84 | PDE2A (0.61) | CES2PDE2ACYP3A4CYP2D6ORAI1 | |
| SCHEMBL7599544 | 0.81 | CES2 (0.47) | CES2PDE2APNMTPTPN5KDM4E | |
| SCHEMBL6679457 | 0.80 | CES2 (0.51) | CES2PDE2AKDM4ECES1ALDH1A1 | |
| SCHEMBL6679460 | 0.80 | CES2 (0.51) | CES2PDE2AKDM4ECES1ALDH1A1 | |
| SCHEMBL6701810 | 0.80 | CES2 (0.51) | CES2PDE2AKDM4ECES1ALDH1A1 | |
| SCHEMBL12868145 | 0.79 | PDE2A (0.46) | CES2PDE2APTPN5ALDH1A1KIF11 | |
| SCHEMBL12388640 | 0.79 | PDE2A (0.55) | CES2PDE2APNMTPTPN5KDM4E | |
| SCHEMBL2957243 | 0.79 | CES2 (0.46) | CES2PDE2APTPN5HSD17B10IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210198285-A1 | Method for Producing an Organic Electronic Component, and Organic Electronic Component | NOVALED GMBH (DE) | 2021-07-01 | — | — | US | disclosed |
| US-8298830-B2 | Organic materials able to detect analytes | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-10-30 | — | — | US | disclosed |
| US-20100310424-A1 | ORGANIC MATERIALS ABLE TO DETECT ANALYTES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-12-09 | — | — | US | disclosed |
| US-7759127-B2 | Organic materials able to detect analytes | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-07-20 | — | — | US | disclosed |
| US-7700366-B2 | Fluorescent, semi-conductive polymers, and devices comprising them | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-04-20 | — | — | US | disclosed |
| US-20060073607-A1 | Organic materials able to detect analytes | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-04-06 | — | — | US | disclosed |
| US-20050196775-A1 | Fluorescent, semi-conductive polymers, and devices comprising them | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2005-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210198285-A1 | Method for Producing an Organic Electronic Component, and Organic Electronic Component | AP2M1, OR10J3, OPRM1 | CES2 1506/4885PDE2A 4862/4885PNMT 315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.