Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.95 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.95 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.95 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL358811 | 1.00 | POLB (0.95) | POLBALDH1A1TDP1L3MBTL1GRIN2D | |
| Hydrochloric Acid SCHEMBL31013084 | 0.98 | POLB (1.00) | POLBALDH1A1TDP1L3MBTL1GRIN2D | |
| Bromide SCHEMBL20984100 | 0.98 | POLB (0.91) | POLBALDH1A1TDP1L3MBTL1GRIN2D | |
| Hydrochloric Acid SCHEMBL1408149 | 0.98 | POLB (1.00) | POLBALDH1A1TDP1L3MBTL1GRIN2D | |
| Methyl Alcohol SCHEMBL28589868 | 0.94 | ALDH1A1 (0.84) | POLBALDH1A1TDP1L3MBTL1GRIN2D | |
| Phosphoric Acid SCHEMBL20984218 | 0.88 | POLB (0.75) | POLBALDH1A1TDP1L3MBTL1GRIN2D | |
| Oxalic Acid SCHEMBL20984131 | 0.88 | POLB (0.75) | POLBALDH1A1TDP1L3MBTL1MEN1 | |
| Sulfuric Acid SCHEMBL20984884 | 0.88 | POLB (0.75) | POLBALDH1A1TDP1L3MBTL1GRIN2D | |
| Nitric Acid SCHEMBL20984720 | 0.85 | POLB (0.70) | POLBALDH1A1TDP1L3MBTL1GRIN2D | |
| SCHEMBL2746683 | 0.83 | ALDH1A1 (0.68) | POLBALDH1A1TDP1L3MBTL1GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4442318-A2 | HETEROCYCLIC INHIBITORS OF MCT4 | Vettore, LLC (US) | 2024-10-09 | — | — | EP | disclosed |
| CN-111278821-B | Spiro compounds as farnesol X receptor modulators | 百时美施贵宝公司 | 2023-10-03 | — | — | CN | disclosed |
| WO-2022040157-A1 | BORON CONTAINING COMPOUNDS AND THEIR USES | 5METIS, INC. (US) | 2022-02-24 | — | — | WO | disclosed |