Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23628934 | 0.89 | ALDH1A1 (0.59) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL26483425 | 0.87 | MAPT (0.60) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL7428427 | 0.86 | MAPT (0.72) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL23292304 | 0.82 | WDR5 (0.62) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL29994410 | 0.82 | WDR5 (0.62) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL23928013 | 0.81 | MAPT (0.55) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL24266512 | 0.81 | NPC1 (0.61) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL26494892 | 0.81 | KMT2A (0.44) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL18113478 | 0.80 | MAPT (0.61) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL29717296 | 0.79 | MAPT (0.59) | MAPTMEN1KMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4199919-A1 | COMPOUNDS AS GLP-1R AGONISTS | Terns Pharmaceuticals, Inc. (US) | 2023-06-28 | — | — | EP | disclosed |
| WO-2022040600-A1 | COMPOUNDS AS GLP-1R AGONISTS | TERNS PHARMACEUTICALS, INC. (US) | 2022-02-24 | — | — | WO | disclosed |