Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | WDR5 | P61964 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14377108 | 0.90 | MAPT (0.63) | MAPTALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL23628934 | 0.88 | ALDH1A1 (0.59) | MAPTALDH1A1SMN1; SMN2MAPK1GAA | |
| SCHEMBL29994410 | 0.86 | WDR5 (0.62) | MAPTALDH1A1SMN1; SMN2MAPK1GAA | |
| SCHEMBL23292304 | 0.86 | WDR5 (0.62) | MAPTALDH1A1SMN1; SMN2MAPK1GAA | |
| SCHEMBL4589191 | 0.86 | MAPT (0.59) | MAPTALDH1A1SMN1; SMN2MAPK1GAA | |
| Tert-Butyl Formate SCHEMBL27868028 | 0.81 | MAPT (0.54) | MAPTALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL29574091 | 0.81 | MAPT (0.58) | MAPTALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL4843935 | 0.80 | KDM4E (0.53) | MAPTALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL16774886 | 0.79 | HTR3E (0.59) | MAPTSMN1; SMN2CYP2C19KDM4ELMNA | |
| SCHEMBL22471135 | 0.79 | MAPT (0.60) | MAPTALDH1A1SMN1; SMN2MAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12391727-B2 | Traceless reductively cleavable linker molecules for peptide purification | Gyros Protein Technologies AB (SE) | 2025-08-19 | — | — | US | disclosed |
| US-12269845-B2 | Traceless reductively cleavable linker molecules for peptide purification | Gyros Protein Technologies AB (SE) | 2025-04-08 | — | — | US | disclosed |
| CN-118373769-A | Compounds and methods for peptide purification | 格瑞罗斯普罗泰恩科技公司 | 2024-07-23 | — | — | CN | disclosed |
| CN-118373757-A | Compounds and methods for peptide purification | 格瑞罗斯普罗泰恩科技公司 | 2024-07-23 | — | — | CN | disclosed |
| CN-118373759-A | Compounds and methods for peptide purification | 格瑞罗斯普罗泰恩科技公司 | 2024-07-23 | — | — | CN | disclosed |
| CN-118373758-A | Compounds and methods for peptide purification | 格瑞罗斯普罗泰恩科技公司 | 2024-07-23 | — | — | CN | disclosed |
| US-20240116981-A1 | TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES FOR PEPTIDE PURIFICATION | Belyntic GmbH (DE) | 2024-04-11 | — | — | US | disclosed |
| CN-112638864-B | Traceless reductive cleavable linker molecules for peptide purification | 格瑞罗斯普罗泰恩科技公司 | 2024-03-08 | — | — | CN | disclosed |
| EP-4219446-A2 | TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES FOR PEPTIDE PURIFICATION | Gyros Protein Technologies AB (SE) | 2023-08-02 | — | — | EP | disclosed |
| US-20210332082-A1 | TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES FOR PEPTIDE PURIFICATION | Belyntic GmbH (DE) | 2021-10-28 | — | — | US | disclosed |
| CN-112638864-A | Traceless reductively cleavable linker molecules for peptide purification | 贝兰迪克有限责任公司 | 2021-04-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12391727-B2 | Traceless reductively cleavable linker molecules for peptide purification | VIP, NGLY1, HM13 | MAPT 1722/4885ALDH1A1 1635/4885SMN1; SMN2 4531/4885 |
| US-20210332082-A1 | TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES FOR PEPTIDE PURIFICATION | VIP, NGLY1, HM13 | MAPT 1722/4885ALDH1A1 1635/4885SMN1; SMN2 4531/4885 |
| US-12269845-B2 | Traceless reductively cleavable linker molecules for peptide purification | VIP, NGLY1, HM13 | MAPT 1722/4885ALDH1A1 1635/4885SMN1; SMN2 4531/4885 |
| US-20240116981-A1 | TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES FOR PEPTIDE PURIFICATION | VIP, NGLY1, HM13 | MAPT 1971/4885ALDH1A1 1725/4885SMN1; SMN2 4462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.